May of of interest~

[BPleasant]

Ran across this while surfing...
People stop drinking alcohol when they switch off one hunger hormone called ghrelin, new study - Worldnews.com


People stop drinking alcohol when they switch off one hunger hormone called ghrelin, new study The Examiner 2009-12-31
Dec. 31 - According to the latest "A Faculty of 1000: Biology and Medicine" evaluation, the new study done by the research scientists at the University of Gothenburg in Sweden examined how one stomach-produced hormone influences the desire to eat and also consume alcohol could be switched off to control drinking problems. The study, carried out by Jerlhag et al. at the University of Gothenburg in Sweden, showed that the hormone ghrelin,...

How a stomach hormone, ghrelin influences desire to drink alcohol, new study

[Montana Mommy]

May of of interest~

if you could explain this a little more it would make more since to me.

[BPleasant]

May of of interest~

The sentences in blue are links to the articles.


How do you stop your desire to drink alcoholic beverages? This intriguing paper suggests that the hormone ghrelin facilitates in mice the motivation to drink alcohol (in addition to its well-known role in strengthening the motivation to eat food).

Ghrelin is a hormone typically released from the stomach into the bloodstream at the beginning of meals that is known to promote appetite and food intake. Here, one of the study's authors, Jerlhag E, and colleagues report that it may also promote alcohol intake.

Scientists revealed how microinjections of ghrelin into the ventral tegmentum or into cerebral ventricles increased behavioral consumption of alcohol. On the opposite side, microinjections or systemic administration of receptor-blocking antagonists reduced alcohol consumption.

This may reflect more than an appetite for calories, because the authors report that mutant knockout mice lacking GHS-R1A ghrelin receptors further showed deficits in alcohol-induced conditioned place preference, and related stimulation of dopamine release in the nucleus accumbens. The big question here is do these results suggest a role for the effects of ghrelin on the brain in the motivation for alcohol consumption?

According to the latest study, "Requirement of central ghrelin signaling for alcohol reward," published in the Protocols of the National Academy of Sciences, U S A. 2009 Jul 7;106(27):11318-23. Epub 2009 Jun 29. (authors) Jerlhag E, Egecioglu E, Landgren S, Salom? N, Heilig M, Moechars D, Datta R, Perrissoud D, Dickson SL, Engel JA., Section for Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, SE-405 30 Gothenburg, Sweden.

[rubywillow]

May of of interest~

Interesting. Considering the cost to society of alchol-related problems, one would think it would be a higher priority for research. Many believe the social and financial profits to the alcohol industry influence governments NOT to pursue more studies, cures, treatments.

[Meech]

May of of interest~

Ruby Willow,

Isn't that a scary thought. We don't want to believe that governments do NOT want to pursue more studies but we have seen that happen in many other industries haven't we? Where big companies' money control what gets done (or researched) and innocent people are suffering as a result. Hopefully these kind of findings reach a high enough public awareness to put some pressure on those that run our countries.

Good info here!