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    More on Neurotransmitter activity

    I received this via email today and wanted to share..:h

    I just received this in my email about neurotransmitters and wanted to share in light of Susan's experience.

    When Neurotransmitters Are Depleted, What Happens To Our Bodies?
    Any type of Stress causes the OPIOID levels to diminish. This creates a sense of urgency in an individual. A person also becomes irritable, easily angered, easily loosing their temper.

    Many people find relief from these feelings from an artificial opioid that is released by Alcohol or other drugs.

    Low OPIOID levels automatically causes an increase in DOPAMINE release. This causes a feeling of alertness and anxiety. Continued Dopamine release causes emotional fatigue.

    When Dopamine is released, it is exactly the same chemical response as that following a small cocaine use. (The greatest natural Dopamine release happens at the moment of sexual climax.)

    Low OPIOID levels also causes the lowering of the GABA levels. When this occurs, feelings of anxiety, insecurity and unexplained panic are felt.


    The most obvious feeling is deep Depression.
    Low GABA levels cause an increase in NOREPINEPHERIN release . . .

    This encourages quick, emotional response like anger and discourages slower, deliberate (logical) thinking.

    High NOREPINEPHERIN causes ADRENALINE to be released, which cause the heart to beat both faster and harder and causes red corpuscle reserves to be placed in the blood stream.

    It also causes energy sources, nutrients, and oxygen to be diverted from functional organs straight to the muscles.

    Here is where High Blood Pressure, Strokes and damage to a number of pressure sensitive organs occurs. (The continued diversion of oxygen and nutrition from the functional organs causes them to become diseased.)

    Low GABA levels causes a decrease in SEROTONIN levels which makes sleep difficult to impossible. This person also exhibits feelings of irritability and a lack of rational emotion.

    The SEROTONIN reduction further pushes the OPIOID levels lower. Thus, the Stress Cycle repeats with continually increasing intensity.

    In the stress cycle "feedback" loop, the following reactions occur, all of which are obviously useful to a person threatened by a predator or a mortal enemy. They are harmful to the modern person under long term stress as exemplified by the statements :


    Stress causes the opioids (endorphin, enkephalin, etc.) levels to diminish. The lower opioids levels create a sense of urgency. This sense of urgency is usually expressed as the need to respond to certain physical demands, e.g., if one drinks a couple of quarts of iced tea at 10:00 in the evening, he or she will usually awaken in the middle of the night with a very strong sense of urgency.

    As soon as the body's need has been taken care of, the sense of urgency goes away.
    If the sense of urgency is initiated by continuing stress and there is no way to relieve it . . . the stress "signal" goes from the opioids to GABA to Norepinephrine to Serotonin to Opioids to, etc., and, a loop occurs.

    The result is a continued diminishing of the chemicals until the system's control of emotions is lost. The individual first becomes irritable, easily angered and finds him or herself suffering from easy loss of temper.

    Many find relief in the artificial opioid released by alcohol, tetrahydroisoquinoline, and thus become alcoholics.

    Others turn to opiates such as heroin, morphine, etc. Some find relief in carbohydrate bingeing.


    Most, rather noisily, just ruin their careers and their marriages.

    The lowering of the opioids causes an increase in dopamine levels and a decrease in GABA levels.
    This produces a combination of alertness and anxiety. [The so called adrenaline rush is in large part the feeling of exhilaration caused by the dopamine release. It is exactly the same chemical response as that following a small cocaine use. (i.e. cocaine use causes dopamine to be released in larger amounts than the body requires for normal functioning such as sexual climax or appreciation of beauty.)

    Continual extra dopamine release causes emotional fatigue which can become debilitating. It can also lead to anhedonia, in which case, he or she can no longer enjoy beauty, music, or even love, in the extreme case. Continuous anxiety from GABA reduction can lead to depression and feelings of inadequacy.]


    The lowering of the GABA levels causes the norepinephrine levels to increase and serotonin to decrease.
    The increase in norepinephrine causes adrenaline to be released and the reduction of serotonin makes sleep difficult to impossible.

    [It is important to note that serotonin is a sleep enabling neurotransmitter, not a sleep inducing one. A lack of serotonin makes sleep very hard to achieve. Once the serotonin becomes available, the body demands the sleep it now badly needs. When this has been done the person feels rested and Fully refreshed. However, if the stress feedback continues, the lack of sleep can cause a great deal of damage to the body.]


    The increased norepinephrine encourages a quick, emotional response (e.g. anger) and discourages slower, deliberate (logical) thinking. [The anger released by the lack of the opioids is triggered more rapidly in the presence of the norepinephrine.]

    The adrenaline release causes the heart to beat both faster and harder and causes red blood cell reserves to be placed in the blood stream. It causes energy sources, nutrients, and oxygen to be diverted for use by the muscles.
    This deprives functional organs such as the liver, the digestive tract, etc., from their needed resources. This results in the person being able to make an almost super human (though perhaps illogical) physical response to the threat.

    [When the heart is required to beat faster and harder over long periods of time, the illness commonly known as High blood pressure usually follows. Unfortunately, this condition is usually not reversible. In the extreme case, this condition can cause strokes and damage to a number of pressure sensitive organs and passages. It can also cause damage to the heart. Further, the continual diversion of oxygen and nutrition from the essential organs causes those organs to become diseased.]


    The norepinephrine increase causes the serotonin levels to decrease. This makes sleep difficult or impossible. The serotonin reduction further modulates the opioids downward. The cycle therefore repeats with continually increasing intensity.

    It becomes obvious that the proper balance of Neurotransmitters to each other is as important as the neurotransmitter production. Neu-BeCalm'd? is formulated to give your body the proper nutrition to balance and produce neurotransmitters.
    Decades of university research have been required to find the means by which the "cycle" is kept from repeating over and over. If this cycle were not brought under control grave illness would obviously occur as it does when we are under unrelenting stress.

    As early as 1928, Dr. Hans Selye's research showed that when stress is long term in nature, the "stress management chemicals" (as he called them), which enable the body to maintain control, are depleted. Ultimately, the correction can no longer be made. Selye showed that once these chemicals are totally depleted, the subject dies!

    The last 20 years of research by many notable scientists such as Dr. Gerald Kozlowski, Dr. Terry Neher, and Dr. M. L. Barbaccia found that the stored metabolites can be replaced from normal diet, but only very slowly.

    They further found that the slowness was not due to a "lack of production facility" but rather a "lack of raw materials". While the quantities required vary from one individual to another, getting these additional nutrients from food is difficult.

    The average person would require several pounds of exotic fish, a quart of milk, and a variety of other high cholesterol and high fat content foods daily.

    Thus, condensed supplementation is required to allow replacement of the necessary metabolites during modern times of continuing stress. This can be done by taking each of the individual supplements individually or by taking a single capsule containing all of them. The supplements must contain: d/l-phenylalanine and l-glutamine in combination with Vitamin B6, Calcium, Magnesium, and Folic Acid in proper proportions. This formulation of amino acids, vitamins, and minerals, has been shown to enhance the opioids, GABA, dopamine, norepinepherine, and serotonin availability.
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