I'm a single 41 y.o. male who has been drinking heavily for 20 years, and my current intake is extremely high. I drink 24-25 units (19-20 "standard drinks") every night, and spend most of the next day sobering up. I can't hold down a job anymore and I'm destroying my health at a rapid rate. It's basically an obsessive-compulsive type of ritual for me now, but it began in my early 20's as an attempt to try to cope with deep shyness, and the loneliness and depression that occurred as a result of that shyness. I don't have any other mental health issues and don't have a problem with any substance apart from alcohol (I don't even smoke cigarettes). Alcohol is now a curse and is stopping me living a normal life or enjoying much in life, and the loneliness is only made worse by it. I have tried many ways of addressing this over the years, including numerous AA meetings, counselling, CBT, psychiatrists, numerous anti-depressants, several detoxifications, periods of abstinence, disulfiram (Antabuse), acamprosate calcium (Campral), naltrexone used in a non-Sinclair way, and occasionally low-dose cannabis as an emergency substitute/stabiliser while trying to remain sober and fight off desperate cravings. Please note that I don't promote the recreational use of illegal drugs and am not a regular user of them. I am now investigating baclofen aswell as gabapentin and other newer-generation anticonvulsant drugs, including topiramate, as possible new ways of beating alcoholism.
The results from my previous attempts have been mixed, but Campral did seem to help me feel a sense of stability and reduced craving for alcohol AFTER detoxification. I stupidly decided that Campral wasn't helping me much, but after a few days of discontinuing it, my emotional instability and cravings for alcohol greatly increased...so please don't dismiss it as quickly as I did. Cannabis helped as an immediate rescue from extreme craving and depression during and soon after detox, but again I'm not here to promote the use of an illegal substance, and I have personally seen very heavy use of cannabis induce tolerance to it and the reduction/elimination of any helpful effects in some of my friends (this does not seem to happen with controlled and sensible use). Naltrexone never helped apart from when I drank after taking it, which is why I have been interested in the Sinclair method of "pharmacological extinction", but it's blocking of the opioid/endorphin pleasure receptors of the brain has made me wary of trying it, as I am often dysphoric/depressed. I have also heard of the anti-nausea drug ondansetron being useful in the treatment of alcohol cravings after detox.
I may not log in here on a daily basis, so if anyone replies to this, please don't think I'm ignoring you if I don't reply straight away.
Best wishes to all,
Greg
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