Chantrix

[Lucylookingforhelp]

Does anyone have comments on success with Chantrix?

[cyclefan]

Chantrix

Hi Lucy

I used Chantix to stop smoking two years ago. I considered it a miracle drug as I had smoked for 34 years and nothing before had helped. I am now 2.5 years since I last smoked and I don't miss it at all.

Please be aware that there are warnings against using this drug if a person has issues with depression, and it does not interact well with certain anti-depression medications. Make sure your health care provider is well aware of your medical history and any other drugs you are taking.

Good luck with stopping smoking, I know how difficult it can be.

[cowgal]

Chantrix

Heard it works

I have a friend who used it to quit, it made her really not enjoy the act of smoking.......she as able to quit in days after she started on it, don't smoke, but it was a miracle for her!

MA

[Lucylookingforhelp]

Chantrix

I should clarify...

anyone have success with Chantix for alcoholism? Thank you everyone for your inuput. : )

[Angelcakes]

Chantrix

I know someone that used Chantix to be al & nic free for the first 30 days. She felt the al & nicotine reward centres in the brain were the same (only smoked when she drank) It helped her immensely.
Hope that helps.

[Lo0p]

Chantrix

Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers
Biological Psychiatry, Volume 66, Issue 2, 15 July 2009, Pages 185-190
Sherry A. McKee, Emily L.R. Harrison, Stephanie S. O'Malley, Suchitra Krishnan-Sarin, Julia Shi, Jeanette M. Tetrault, Marina R. Picciotto, Ismene L. Petrakis, Naralys Estevez, Erika Balchunas

Background
Alcohol and tobacco dependence are highly comorbid disorders, with preclinical evidence suggesting a role for nicotinic acetylcholine receptors (nAChRs) in alcohol consumption. Varenicline, a partial nicotinic agonist with high affinity for the α4β2 nAChR receptor, reduced ethanol intake in rodents. We aimed to test whether varenicline would reduce alcohol consumption and alcohol craving in humans.
Methods

This double-blind, placebo-controlled investigation examined the effect of varenicline (2 mg/day vs. placebo) on alcohol self-administration using an established laboratory paradigm in non-alcohol-dependent heavy drinkers (n = 20) who were daily smokers. Following 7 days of medication pretreatment, participants were first administered a priming dose of alcohol (.3 g/kg) and subjective, and physiologic responses were assessed. A 2-hour alcohol self-administration period followed during which participants could choose to consume up to 8 additional drinks (each .15 g/kg).
Results

Varenicline (.5 ? SE = .40) significantly reduced the number of drinks consumed compared to placebo (2.60 ? SE = .93) and increased the likelihood of abstaining from any drinking during the self-administration period. Following the priming drink, varenicline attenuated alcohol craving and reduced subjective reinforcing alcohol effects (high, like, rush, feel good, intoxicated). Adverse events associated with varenicline were minimal and, when combined with alcohol, produced no significant effects on physiologic reactivity, mood, or nausea.
Conclusions

This preliminary investigation demonstrated that varenicline significantly reduced alcohol self-administration and was well tolerated, alone and in combination with alcohol in heavy-drinking smokers. Varenicline should be investigated as a potential treatment for alcohol use disorders.


I have a friend who used it to quit smoking. He said it also reduced his ability to enjoy a beer. But when he tried Chantix he was already cured of his alcoholism via the Sinclair Method. His story is here: thesinclairmethod.com • View topic - Chantix and Naltrexone