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    Baclofen and exercise

    I've noticed a VERY strange but undeniable effect while exercising on baclofen. According to the warnings, we're supposed to avoid activities that might require muscle tone while taking baclofen. Initially, I tried to do this, but I exercise twice a day sometimes. Cardio in the morning, always, and weightlifting in the evening. I tried to take all of my baclofen right before weightlifting so that it wouldn't hit my bloodstream till I was done but this didn't work out. I couldn't get enough in.

    I'd never noticed any of the muscle-relaxant properties of the bac before so I decided I'd just take it all day before and after exercising and see what happened. The results have me absolutely confounded. (skip ahead of the quote for the results)

    This is a description of one of the exercises I do regularly:

    Lo0p wrote: I finally noticed the benefits of opioid receptor upregulation earlier this week.

    One of my training days is leg day, and we all hate leg day. Your legs have some of the biggest and strongest muscles in your entire body. The difference between training your legs and any other part of your body is this: your legs will do what you ask them to do. If you are training something like your chest doing bench presses, there comes a point at which after 8 or so repetitions that you just cannot physically push anymore. This is called failure. With legs it's different. I can load up the barbell with my weight in plates and do 4 sets of 12 reps of barbell squats and call it a great exercise, and it is. A barbell squat is where you place the barbell on your shoulder blades and lower yourself down as though you were sitting down and then stand back up. It is a brutal, full body exercise. It feels like you just sprinted a 100yd dash. But you can also do more. I can load up the same weight and go 4 sets for 20 reps too. This intensifies the exercise by a factor of way more than 2. By the time I'm done I'm begging for life and feel like I've just climbed Mt. Everest in 12 minutes flat.

    When I finally finished I limped back to my car and started sipping on a shake. I didn't really think it was safe to drive for a while so I just sat there trying to catch my breath and relax. Then my whole body got warm and a state of extremely pleasurable deep relaxation set in. Five minutes later I literally thought I was floating. I knew that I had to get home soon to eat on schedule so I broke my own rule. For the first time, in a very long time, I drove intoxicated. :lol:

    Why do this? When you put your body in a state of shock by doing extremely heavy full body resistance/endurance exercises it responds as though it's been injured (it has). When you go to sleep it stimulates the production and release of Human Growth Hormone. This stuff is literally like drinking from the fountain of youth. It promotes fatty acid oxidation and lean mass synthesis. It stimulates the destruction of old cells and the production of new ones. These alone are huge but they are just a couple of the effects of HGH among a myriad of other extremely beneficial processes.

    Here is a youtube video of someone demonstrating the barbell squat: http://www.youtube.com/watch?v=40p1qQZTNRw[/video]]YouTube - Fitness Tips with Chrissy: The Barbell Squat

    Normally I do 4x20 squats with the same weight every time because I'm doing them as part of a cutting protocol and am not trying to increase my strength I'm just trying to keep the muscle mass I have while cutting fat. It's a beast of an exercise and it kicks my butt every time.

    Now here's what happened after switching the baclofen to before my workout:


    Normal Week: 4x20 @ 165 lbs = 13200 lbs moved

    Week 1: Did 3x20 at my normal weight and was really astounded because I wasn't winded at all. I was really confused...I've done this exercise a hundred times and it always kicks my butt. Usually I have to sit down on the ground to rest after every set! So I threw an extra 10 lbs on and finished my last set...but I still felt like I hadn't even been challenged. Perplexing. 13400 lbs moved

    Week 2: Started @ plus 10 lbs and did 5x20 = 17500 lbs moved. I am SHOCKED!! This is inexplicable I felt like I could have done even more!

    Week 3: Started at plus 30 lbs and did 5x20 = 19500 lbs moved! Easily!!

    I am intimately familiar with how much weight I can lift and this makes absolutely NO sense at all!!!!


    Something is going on here! On top of all of this, I am on a freaking DIET! Which means I am not even consuming enough calories to maintain my body weight . There is no way on earth I should be getting this much stronger.

    I also have been going for 60 minutes in my AM cardio instead of 45 for the entire last week for absolutely no reason at all other than I just didn't feel like stopping. Really...NO REASON. I have cut (dieted) many times and get fantastic results going for just 45 minutes of fasted AM cardio combined with my nutrition protocol and resistance training.

    Thoroughly confused...Has anyone else noticed anything like this??
    :nutso: I take pride in my humility :nutso:
    :what?:
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    #2
    Baclofen and exercise

    Funny

    great stuff as usual loop!!:goodjob: I never worried about dosing/timing(not til I got this new batch which is kicking my a*s somnolence wise). I usually work out every morning, weights then cardio, weights every other day, chest/triceps then back/biceps, then shoulders..... Do legs & abs every day....... Have(or seem to) much more stamina than before, but maybe since I am not overdoing al intake?!

    Since on bac, I notice I can lift SO much more weight! My muscles are more defined & you'd think w/ a muscle relaxant the opposite would happen?!?!

    Very interesting thread, great, just my kind of thing! Exercise addict of sorts...... Beats other addictions, right?!

    MA
    :rays:My happiness is my greatest gift to others:rays:eace:

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      #3
      Baclofen and exercise

      Hey Loop,
      Very interesting reading!! I don't do as much as you and Cowgal, but I do run a lot.
      I have found running easier....but again that could be because I am not drinking as much AL.
      Could it be that because Bac is a muscle relaxant, that your muscles don't have as much 'resistance' in them to the exercise???
      Also, I thought we were supposed to exercise more than we did before taking Bac, so that we didn't have muscle degeneration....??
      Sounds like you are reaping the benefits no matter what though...good for you!!
      Amelia

      Sober since 30/06/10

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        #4
        Baclofen and exercise

        I can agree that the body gets stronger without AL. It happens effortlessly, even on a bad nights sleep. On Saturday I easily did 45 minutes on the treadmill when usually I do 30 minutes. I just think the body says AHHHHH when it no longer has to work so hard to get rid of toxins.
        Wow you are strong!
        Success is not final, failure is not fatal, it is the courage to continue that counts.
        AF since May 6, 2010

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          #5
          Baclofen and exercise

          Tulipe;777904 wrote: I can agree that the body gets stronger without AL. It happens effortlessly, even on a bad nights sleep. On Saturday I easily did 45 minutes on the treadmill when usually I do 30 minutes. I just think the body says AHHHHH when it no longer has to work so hard to get rid of toxins.
          Wow you are strong!

          I've done these routines with and without AL before. There simply is nothing that I can attribute this undeniably significant difference to other than bac.

          I forgot the strangest part too!

          When you exercise, if you do so to the point that your respiratory and cardiovascular systems can no longer supply your muscles with the oxygen needed to perform the work, then your body switches fuel sources. Instead of burning oxygen it burns a fuel called glycogen. This is when your muscles burn. In burning glycogen for energy instead of oxygen a byproduct starts to build up called lactic acid. This causes the burning sensation in the first place but it also doesn't get flushed out of your muscles as readily as other things. It sticks around and over the course of days it forms lactic acid crystals. These are what makes your muscles sore. Your cardiovascular system is also charged with eventually flushing these crystals out and causing recovery from the pain over the course of days.

          Normally, this "leg day" will have me so sore that I walk around in a pretty significant amount of pain for the entire week until I do it again. The first couple of days I can barely walk. Climbing stairs is almost impossible and lowering myself down on the loo is the stuff of youtube fame. :H This is unavoidable for me and yes it is annoying but the benefits far outweigh the pain.

          I HAVEN'T BEEN SORE IN THREE WEEKS!!
          Again...inexplicable.
          :nutso: I take pride in my humility :nutso:
          :what?:
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            #6
            Baclofen and exercise

            Ahaa!

            Found this this morning:

            Int J Sports Med 1997; 18: 75-78 wrote: ? Georg Thieme Verlag Stuttgart ? New York


            Administration of a GABAB Agonist Baclofen Before Running to Exhaustion in the Rat: Effects on Performance and on Some Indicators of Fatigue

            A. Abdelmalki, D. Merino, D. Bonneau, A. X. Bigard, C. Y. Guezennec
            Institut de M?decine A?rospatiale du Service de Sant? des Arm?es, Br?tigny sur Orge, France

            The present study was designed to examine the effects of administration of a GABAergic agonist (Baclofen) on run-time to exhaustion in trained and untrained rats, and on some indicators of fatigue. Run-time to exhaustion on a treadmill set at a speed of 25 m ? min-1 was significantly increased in both untrained (p < 0.01) and trained rats (p < 0.005) administered with baclofen one hour before the exercise. The animals who had nun the longest time displayed the lowest concentrations of liver and muscle glycogen, and a decrease in plasma glucose concentrations (p
            :nutso: I take pride in my humility :nutso:
            :what?:
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              #7
              Baclofen and exercise

              has it been baned from professinal sports lo0p?
              you may find something down that path.
              AF since 10/26/2009

              It will be five years sober 10/26/2014

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                #8
                Baclofen and exercise

                brilliant!!

                Worked out today again, lifted way more...................but the foot and calve leg cramps had me cut out my workout.....................anyone else have that problem??? Loss of electrolytes due to kidney output??? Just putting it out there.........................

                MA
                :rays:My happiness is my greatest gift to others:rays:eace:

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                  #9
                  Baclofen and exercise

                  thanks zen

                  you are so helpful in so many ways...................feel like having company in a week?? Am heading down that way.................is it warm tho?? Would love some sun at the beach.............taking potassium, but probably not enough, started higher doses of magnesium and drinking more tonic water, w/ quinine in it...............hope it helps, cuz this sucks!!! I really get off on my workouts,(didn't sound too proper!?) the endorphins you know!!??:H:H:H

                  thanks again wise Zen............................:thanks::thanks:

                  xoxoxo :l

                  MA
                  :rays:My happiness is my greatest gift to others:rays:eace:

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                    #10
                    Baclofen and exercise

                    It's not on the IOC's list of banned substances...but it should be.

                    From my personal experience this is no small effect. This would give someone in an endurance sport a major edge.

                    I just set a personal best for deadlifts (while dieting) tonight.
                    :nutso: I take pride in my humility :nutso:
                    :what?:
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                    Graph of My Drinking From July '09 to January '10

                    Consolidated Baclofen Information Thread




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                      #11
                      Baclofen and exercise

                      zen??

                      just re-read your post, started topa??? That did majorly strange things to me..........made me not drink as much, but I mean, talk about DITZY!!!???I would go blank when talking to people, and I had to give talks, I mean embarrassing!!! Be careful w/ that, but every body is different, you may react to it just fine, I have some folks, LUV, and others who it works great for............personally bac is for me..............just really didn't take enough yesterday, bad day, beside the point.......................good luck, had no clue (you probably wrote somewhere but I missed it) that you d/c'd bac.................well, thanks for all your help to get me on it!!!!:thanks:

                      love ya!!!:l:h

                      MA
                      :rays:My happiness is my greatest gift to others:rays:eace:

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                        #12
                        Baclofen and exercise

                        I think maybe Zen took the topa before the bac?

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                          #13
                          Baclofen and exercise

                          oh

                          thanks for the info..................how are you dolly!!?? :h

                          MA
                          :rays:My happiness is my greatest gift to others:rays:eace:

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                            #14
                            Baclofen and exercise

                            Very Interesting

                            I have just found this thread today.....bit slow, but better late than never.

                            I havent had much desire to exercise at all, but i dont know if its because Im so :durn: tired or its so :durn: hot - I live in the tropics. I go for a "stroll" every morning with my old fat Lab (and I mean every morning, hell we even went on Christmas day - she loves it so much), by the time i get back at 7am, its pretty hot and humid. Thats my excuse anyway.

                            Anyway I am still titrating up on Baclofen, so that may be why, once I hit my switch and can plateau it out, perhaps this somnolence will subside and I will join you happy exercisers.
                            Time to whip AL's Ass :b&d:
                            :h ya
                            Trix

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                              #15
                              Baclofen and exercise

                              great!!

                              Thanks loop!!! You r the best!!

                              off to the gym but will definitely be back to check this out!!

                              MA
                              :rays:My happiness is my greatest gift to others:rays:eace:

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