Baclofen Dosage 'Poll'

[eight days a week]

Baclofen Dosage 'Poll'

Virgil;801365 wrote: Hi 8,

In the opening post of this thread, I did say "Simply indicate in your reply at which one of the baclofen dosage ranges below did you experience the 'switch' for alcohol reduction...". So, I think it's best if the thread remains as is. However, I have another suggestion - should I start another thread entitled "Did baclofen work for you?" (or words to that effect). People could simply indicate a 'Yes' or 'No' but then go on to explain in more detail about their personal experience, if they wish.

What do others think of this idea? I will only proceed if there is a general consensus (say 70% in favour) that it is worth pursuing.

V.

Quite agree V, and I don't mind either way, it was just a thought

As for other threads, some good ideas have been suggested.

I've been finding the on-topic posts in this thread very interesting indeed so far, I hope to see more!

[Lo0p]

Baclofen Dosage 'Poll'

Alright I'll weigh in.

Less than 30 mg per day
30 - 50 mg per day
60 - 80 mg per day
90 - 110 mg per day
120 - 140 mg per day
150 - 170 mg per day
180 - 200 mg per day
210 - 230 mg per day
240 - 260 mg per day
270 mg or more per day (300 mgs)

Gender: Vehemently Male :H
Weight: 164.4 lbs

I hit my switch twice. Both times it took me taking 300 mgs for 3 days and on the third day it was like 'click'. I also drank quite a bit for the first couple of days on 300mgs.

My maintenance is currently 175 mgs but I'm experimenting with 150 mgs to see if that will work too. My maintenance seems to be lower with the brand of baclofen called Liofen from Sun Pharm, than with Baclan from Yoo Young Pharm, where it was 200 - 250 mgs. Both are from All Day Chemist, the cheapest on the net I believe. This may be due to other factors though, I am unsure.

[beatle]

Baclofen Dosage 'Poll'

So, if you are 75kg, that means your switch was at 4mg/kg, right? Obviously that is over the range of the protocol given by Dr. A, but it has worked fabulously for you... so I hope everyone not reaching their switch at 2-3.5mg/kg will take notice (myself included).

[christyacc]

Baclofen Dosage 'Poll'

Less than 30 mg per day
30 - 50 mg per day
60 - 80 mg per day
90 - 110 mg per day
120 - 140 mg per day
150 - 170 mg per day
180 - 200 mg per day
210 - 230 mg per day
240 - 260 mg per day
270 mg or more per day

[beatle]

Baclofen Dosage 'Poll'

christy, does that mean you reached your switch at 90-110mg per day?

[Virgil]

Baclofen Dosage 'Poll'

Virgil;801365 wrote: Hi 8,

In the opening post of this thread, I did say "Simply indicate in your reply at which one of the baclofen dosage ranges below did you experience the 'switch' for alcohol reduction...". So, I think it's best if the thread remains as is. However, I have another suggestion - should I start another thread entitled "Did baclofen work for you?" (or words to that effect). People could simply indicate a 'Yes' or 'No' but then go on to explain in more detail about their personal experience, if they wish.

What do others think of this idea? I will only proceed if there is a general consensus (say 70% in favour) that it is worth pursuing.

V.

Hi Folks,

I have decided not to pursue my suggestion of a new thread entitled "Did baclofen work for you?". Just thought I should let you all know.

V.

P.S. Despite what I said above, I have now started a thread entitled Have you tried baclofen and did it work for you?

[Virgil]

Baclofen Dosage 'Poll'

Hi Folks,

I thought an interim summary was in order.

With the exception of the lowest dose (less than 30mg per day), there is at least one 'tick in the box' for every baclofen dosage range shown in the first post of this thread. The most ticks (three in each case) are for the 150 - 170mg per day and 180 - 200 mg per day ranges.

It would still be good to gather some more figures. So, for those that have already experienced the 'switch' and those that will do so in the future, please consider adding to this thread.

To all those who have already posted on this thread, a big :thanks:.

V.

[reneesmiles]

Baclofen Dosage 'Poll'

Uh oh... thought 30mg a day was enough... Going up to 40mg a day (drank 3 times already this month... previous months since starting Bac... 1 drink per month).

Female, 5'2 and 130 lbs.

[Virgil]

Baclofen Dosage 'Poll'

reneesmiles;806190 wrote: Uh oh... thought 30mg a day was enough... Going up to 40mg a day (drank 3 times already this month... previous months since starting Bac... 1 drink per month).

Female, 5'2 and 130 lbs.

Hi reneesmiles,

You're still in the 30 - 50mg per day range and so the overall picture remains the same.

Please keep us informed of any further developments.

Good luck!

V.

[Virgil]

Baclofen Dosage 'Poll'

Hi Folks,

Dr Ameisen in his book The End of My Addiction (pages 166 - 167) states "1 to 3 milligrams per kilogram of body weight, shown to suppress motivation to consume alcohol in laboratory animals". This variation in baclofen dosage for a given body weight is reflected in the examples that follow. Two males each weighing 75 kg hit the 'switch' at:

Male 1: 120 - 140 mg per day
Male 2: 300 mg per day (note that this is 4 mg per kg of body weight)

Similarly, two females each weighing 55 kg hit the 'switch' at:

Female 1: 90 - 110 mg per day
Female 2: 150 - 170 mg per day

V.

[beatle]

Baclofen Dosage 'Poll'

I repeat myself...

Yes, very interesting, but I wouldn't agree to saying there is little correlation. Yes, there is great variation, but if you look at most of the switches, I think you will find that there is indeed a correlation. And in fact, your examples evidence this -- those who weighed less hit the switch at less. I doubt a 55kg woman would need to, or more importantly, could have gone up to 300mg/day.

I'm no scentist (that's for certain), but my theory on the variation is that brains that are more depleted (I almost wrote 'deleted'), for whatever reason, need more bac before they hit the switch than those brains that are, for whatever reason, less in need.

Unfortunately, but not surprisingly, I'm afraid I am one of those with the neediest brains and the smallest bodies.

[christyacc]

Baclofen Dosage 'Poll'

I am a female and am up to 200mgs and no switch.

[Virgil]

Baclofen Dosage 'Poll'

beatle;837706 wrote: Yes, very interesting, but I wouldn't agree to saying there is little correlation. Yes, there is great variation, but if you look at most of the switches, I think you will find that there is indeed a correlation. And in fact, your examples evidence this -- those who weighed less hit the switch at less. I doubt a 55kg woman would need to, or more importantly, could have gone up to 300mg/day.

I'm no scentist (that's for certain), but my theory on the variation is that brains that are more depleted (I almost wrote 'deleted'), for whatever reason, need more bac before they hit the switch than those brains that are, for whatever reason, less in need.

Unfortunately, but not surprisingly, I'm afraid I am one of those with the neediest brains and the smallest bodies.

beatle,

Thanks for correcting me. That's why I've now edited my original post.

I'm intrigued by your comment "that brains that are more depleted (I almost wrote 'deleted'), for whatever reason, need more bac before they hit the switch than those brains that are, for whatever reason, less in need". Would you care to elaborate on what you mean by 'depleted' in this context? Depleted of what?

V.

[birdy02]

Baclofen Dosage 'Poll'

Less than 30 mg per day
30 - 50 mg per day
60 - 80 mg per day
90 - 110 mg per day
120 - 140 mg per day
150 - 170 mg per day
180 - 200 mg per day
210 - 230 mg per day
240 - 260 mg per day
270 mg or more per day (270 to be exact)

Gender: Female 41 yrs old
Weight: 163 lbs, 74 Kg

Switch at 3.6 mg/Kg I have no doubt that I reached it. My complete indifference to alcohol constantly amazes me.

My maintenance dose is yet to be decided. I am at 240 mg right now and will start dosing down more in a few more days.

LOL (in admiration) about all the skinny women who are alcoholics! How do you take in all those extra calories and stay small! I am so looking forward to backing off the high dose of Baclofen. I gained about 8-10 pounds while on it but now I can back off and get my metabolism back AND get the big boost of not taking in an extra 1200 alcohol calories a day!!!

I started drinking almost every night when I was about 23 years old (1992 or so). So I guess that puts me at 18 years of alcohol abuse. It wasn't very much at first, but enough to get me intoxicated. Over all the years my intake continually increased. My witching hour is late afternoon and I drink right up until I go to bed. If I can start earlier in the afternoon I will but most of those years I worked a full time day job (I'm a stay at home Mom now) and would start drinking the moment I got home.

I don't know how to calculate units but for the last several years I averaged 9-12 light beers a night. Rarely less than 9 and sometimes more than 12. Sometimes it would be my favorite microbrews (which I like better - they are stronger but more expensive) and often times there would be some wine mixed in there too.

One thing I should add is that I had alcohol tendencies from the first time I put alcohol to my mouth. I have never been a controlled drinker. When I was in college I didn't drink every night but I drank like a fish on the weekends. I am not a person who gradually became an alcoholic. Rather I just resisted doing it every night until I was out of college.

Also, I have serious suicidal-type depression that I have had since childhood. It is well treated and under control with medication (currently Celexa) and has been since the mid-nineties but I'm sure it is somehow mixed into my messed up body chemistry to make me a natural alcoholic - probably from birth. Along with all that I have had plenty of anxiety but depression has been a more serious issue for me than anxiety. Insomnia has always been a problem but is not now with the Baclofen. Prior to that I have used antihistamines, trazadone, ambien, and/or, of course, alcohol to put me to sleep.

Kelly

[Virgil]

Baclofen Dosage 'Poll'

Hi Folks!

Please note the additional requested information in the very first post of this thread; they are shown in green.

When I started this thread, my main interest was the baclofen dosage required to experience the 'switch'. Since then, the thread's scope has broadened. It goes without saying that, if you choose to participate in this exercise, simply provide whatever information you are happy to divulge.

A big :thanks: to all you wonderful people!

V.