Baclofen and hyperactivation in sperm

[Lo0p]

Baclofen and hyperactivation in sperm

Is it just me or has no one actually listened to a word I've said?

Why can't you just tell me I that every time my heart beat for the entire last day was for nothing? Throw a curse word or an insult in there and make it stick. :h

Edit: I'm afraid to even offer my sympathies to your situation for fear that even that would be taken the wrong way. I am truly sorry...

[AllyB]

Baclofen and hyperactivation in sperm

Lo0p;965497 wrote: Why can't you just tell me I that every time my heart beat for the entire last day was for nothing? Throw a curse word or an insult in there and make it stick. :h

Edit: I'm afraid to even offer my sympathies to your situation for fear that even that would be taken the wrong way. I am truly sorry...

I'm not trying to get at you or make you feel bad, just trying to explain why this kind of topic gets so emotive.:l

I'm very grateful to you for looking up the full study. I couldn't find it and reading medical studies is not my forte. I use a diaphragm as contraceptive and while it's never let me down it isn't the most effective type about. The bit I read made me wonder if I'd be best to back it up with something else.

[Seethepony]

Baclofen and hyperactivation in sperm

Anyone know if the spaghetti harvest has started? Cuz I've got some trees out there, sagging...

[Pride before Fall]

Baclofen and hyperactivation in sperm

I think that's not until early October, Pony.

[Lo0p]

Baclofen and hyperactivation in sperm

Okay then, now that we're back on planet earth there's a couple things I need to clear up:

I didn't drink uncontrollably. I was following my personal rule that has always served me very well. I did actually get drunk, and while fun it was still a reminder that that stuff just isn't for me because I'm not an alcoholic. No cravings, no guilt and no remorse. There is no such thing as relapse for me.

Those guys actually did do a very through analysis with their experiment. It was an impressive level of detail. I needed to confine my negative comments about it to how it might relate to fertility, at this stage.

Seethepony;965647 wrote: Anyone know if the spaghetti harvest has started? Cuz I've got some trees out there, sagging...

That depends on the weather doesn't it? How is it out there? :H

[Pride before Fall]

Baclofen and hyperactivation in sperm

A little dry, Loop (al dente). : )

[ignominous]

Baclofen and hyperactivation in sperm

Just how much of the bottle that you cracked open did you drink? Now that we,re back on earth and because I've just woken up again from my second bout of 2 hour sleep and because I've got nothing better to do and because .......

[Lo0p]

Baclofen and hyperactivation in sperm

Pride before Fall;965677 wrote: A little dry, Loop (al dente). : )

Ohhh...Oooo00oohhh...touch?. :surrender:

[Lo0p]

Baclofen and hyperactivation in sperm

ignominous;965694 wrote: Just how much of the bottle that you cracked open did you drink? Now that we,re back on earth and because I've just woken up again from my second bout of 2 hour sleep and because I've got nothing better to do and because .......

It was where my finger is when I started:



It's not a lot (relatively, from what I recall) but I drank it fast. In 4 big shots. I did that because I knew that if I made a drink I would never drink it and if I poured a shot and let it sit for a second I would forget about it and not end up drinking it.

Ahh, the story of my life: A nice ice cold brew sounds amazing (I buy the good stuff now). So I crack one open, take a sip and it's really, really good! Then I forget that I have it and 5 hours later when I'm cleaning up all the beer bottles after my family party I find it, almost completely full. I think to myself "damn, what a waste." Then "Nah, that was a damn good sip." I chuckle softly to myself and then go to bed.

I hope this is appropriate. I go to sleep with this in my kitchen every night. My bedroom is about 8 feet from the kitchen, everybody else sleeps on the second floor. I never, ever think about it. Let alone the bottles of red (my DOC) in my room.

[ignominous]

Baclofen and hyperactivation in sperm

Yo man . Good to see you back.

[Lo0p]

Baclofen and hyperactivation in sperm

:hijacked:

[ignominous]

Baclofen and hyperactivation in sperm

:groupluv:

[terryk]

Baclofen and hyperactivation in sperm

AllyB- I'm no fertility doctor. The abstract says that baclofen increases sperm amount and sperm hyperactivation, but less than GABA. GABA is found naturally in the human body, baclofen is not. Hyperactivation is a state that all sperm go through to successfully fertilize an egg. More sperm and more Hyperactivation seems to mean higher chance of fertilization right? Maybe not.

This article Sperm from Marijuana Smokers Move Too Fast (one of a bunch I've seen) says about the sperm of cannibis smokers:

The samples from both groups were tested for volume, sperm-count-per-unit of seminal fluid, total sperm count, percent of sperm that was moving, velocity and sperm shape. Sperm also were assessed for an important function called hyperactivation (HA), a closely regulated and very vigorous type of swimming that is required as the sperm approaches the egg. The researchers evaluated HA and velocity while the sperm was in seminal fluid and again after washing and incubation, when the dead sperm were eliminated.

Results showed that both the volume of seminal fluid and the total number of sperm from marijuana smokers were significantly less than for fertile control men. Significant differences also appeared when HA and velocity, both before and after washing, were assessed, the study found.

"The sperm from marijuana smokers were moving too fast too early," said Burkman. "The timing was all wrong. These sperm will experience burnout before they reach the egg and would not be capable of fertilization."



So that's some info, hopefully its not erroneous. I think the real issue here is that you do not want to get pregnant right now. I think that it makes sense to take as many precautions as you can to prevent that from happening. That's not even mentioning the possibility of any other effects (high dose) baclofen might have on sperm and the health of a baby produced from it. Just took a quick look here, and I really can't believe that Lo0p hijacked the thread like this, but I hope he's gonna be okay. -tk

[Cinders]

Baclofen and hyperactivation in sperm

OMG lo0p,

I never, ever meant to be mean or demean.

Ever.

I just wanted to convey that those who do not want to have a child based on what is happening in their lives, shouldn't.

Those who do NOT want to be responsible do not want the responsibility of not being responsible.

I would say "been there done that" but I haven't. I have been so blessed in life by being with a man who understands and understood what bringing an unwanted child into this world means.

lo0p, I never meant to "call you out" in anyway.

I just meant to let all of you know that what AllyB was saying wasn't "silly."

I don't blame you for making fun of her post. I understand.

But, at the end of the day, she is talking about a child that needs to be raised and cared for.

Seriouly, lo0p. you are one of my heros.

I am quite serious about that. I never meant to stir up controversy, I just wanted to direct this thread to those who know and do understand.

I would never, ever want you to drink because of me. Ever.

I did not mean my post that way.

I did, sincreley, mean to post that those of you who do not understand what AllyB was talking about, please go somewhere else. She IS talking about something very serious.

Taking care of a person for many, many years.

Okay. I hope I cleared this up.

lo0p, you are amazing. I really and truly care about you and your sobriety. You have given me hope when there was none. You have given many people hope.

I do care about a woman who has concerns about getting pregnant with a child while she is with a person who is going through our addiction.

Much love and respect,
Cindi

[eight days a week]

Baclofen and hyperactivation in sperm

I had hardly any time when I last posted to express how I felt this thread was going, and don't have much more now (for reasons other than alcohol consumption).

But, Lo0p, even though I've known you buddy from a long time ago, I felt exactly as Cinders articulated in her first two posts. I know you're brilliantly creative and funny (in an English sorta way, of course ) but I just honestly didn't know where you were coming from with that post of yours...

I worried about the OP, and thank goodness she's both extremely level-headed and diplomatic...I would have gone absolutely nuts at a response like that, honestly. And an alcoholic new poster coming here for a reply to a simple question like could easily take it the wrong way (as I did, and I'm sober!) - and the possible results don't bear thinking about. You had one (relatively) hard night knowing you could get out of it, but most others visiting here are not so fortunate...

The further explanation was necessary, imho, and made everything clear, so again I thank Cinders for her response, and to you Lo0p for your incredible hard work and effort, which shone through in the end

I won't mention the other things, unless anyone brings them up...I guess they were written in the heat of the moment, and are probably best forgotten. But Lo0p I think you owe Cinders an apology.

The lesson for me is that we can't assume everyone here, even someone who's read almost all our posts online, ever, (as I have Lo0p's), understands where we're coming from. Maybe some of us lack some sort of sense of humour chip, too (I guess I now class myself in that bracket to some extent!) and take things more seriously than they're meant; it's hard not to though if heavy satire's involved.

Terry, so many thanks for posting objectively, again. Lo0p, once more, great work on the research and I hope you understand where I'm coming from. If not, you can just throw a punch at me when I visit the States (and believe me it's coming soon, so you better get in shape if you want to - oh, hang on, how about buying me a doughnut instead? )

Biggest hug to all :l

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