Fast Titration Schedule

[Ne/Neva Eva]

Fast Titration Schedule

Your point is taken, sober. My point was simply that it's one guy, in the last 18 years. That is not to say that there aren't others. I've got to assume there are. The risks are there. If you're a quadriplegic with a lot of other very serious life-shortening physical ailments. None of them related to alcoholism, presumably, unless someone was putting booze in his feeding tube?

Just sayin.

You posted this stuff on a newbie's thread. She hasn't been back to the forum. Re-read the thread. Would you come back? Would you even take the first pill? I'm not sure that I would have and I was pretty darn determined.

I am not suggesting, not even hinting, that the dangers or side effects or anything at all related to taking high-dose-baclofen should be withheld on this forum. BUT everything should be presented with the full story. Some of the recent cautionary tales? They were taking a lot less bac than you are. They had other things going on. They didn't disclose other meds, alcohol intake, or comorbidity in their VERY alarming threads.

Just pointing out the obvious.

I think yours is a very valuable story, Sober. I really appreciate the fact that you understand what you are doing and why. I get the impression those decisions were made with a bit of research to help you make the decision. And that you weighed the odds.
Now you're sober and not craving even though you're titrating down.
I call that a success story.
just sayin
Ne

[Ne/Neva Eva]

Fast Titration Schedule

Jeez, Sober. We cross-posted.
I understand.
I apologize.
Hugs, okay?

I'm really, really sorry.
Karen

[bleep]

Fast Titration Schedule

Sober, it's good to hear you are doing well.

Lucky you were able to tolerate such high doses. Not many could, or would have to take it really slow to get there. How were you splitting your doses at that level, and were there no SE's?

[I-want-to-be-sober]

Fast Titration Schedule

As I wrote in my first post on MWO (https://www.mywayout.org/community/f2...ain-45781.html) I have been in delirium myself from baclofen withdrawal (225mg) so I'm kind of traumatized. I apologize for writing about some very rare worst-case scenarios which is counterproductive, especially to starters. I won't do it in the future.

@bleep: I just took it 4 times a day. Altough the half-life of baclofen is very short it doubles in case of chronic dosing and brain levels drop slower than blood levels. SE's were tolerable, mostly somnolence.

@Karen: Cross-posting is no serious crime, apologize of course accepted.

-Sober

[bleep]

Fast Titration Schedule

Man, I would be a wreck if I took 150mg's in one go. Thanks Sober.

[TracyA]

Fast Titration Schedule

Wow! Thanks for explaining about the dosage and blood levels. It helps with another thread here about taking the bac in bigger chunks.

I didn't think you intended any harm with the other thing. The newcomer isn't posting here, but she is on the baclofen and doing well, that's what a little bird told me anyway.

[I-want-to-be-sober]

Fast Titration Schedule

Down to 150mg, still sober.

[bleep]

Fast Titration Schedule

Good going Sober. Do you plan on going down to zero, or do you envisage a maintenance dose?

[I-want-to-be-sober]

Fast Titration Schedule

I'll stay @150mg for at least a few months.

[bleep]

Fast Titration Schedule

Cool. Let us know how you fare.

I'm really pleased your experiment appears to have worked Sober.

[Ne/Neva Eva]

Fast Titration Schedule


Congratulations, Sober.
I'm going to add you to my mental list of "It worked!"

[I-want-to-be-sober]

Fast Titration Schedule

I have kind of a dilemma and hope you guys could give me some tips / adivce. Altough I thougt I had reached the switch, in fact time showed I didn't. I'm experiencing relapses (luckily "just" with beer and no hard stuff) every 2-3 weeks for a day or two. Those interfere with my life and hurt my loved ones.

For me (ultra) high-dose baclofen does work against craving, but unluckily I'm very sensitive to the pure physical dependence problems some people experience. So I can't take it everyday for longer periods.

One good thing about my high tolerance to GABAergic drugs in general is that I can / could take like ~150mg? baclofen as needed when I experience strong cravings or started drinking already (baclofen + alcohol doesn't mess me more up than alcohol alone). I would combine it with 100mg naltrexone.

The goal is to either stop the urge to drink or at least the loss of control in case of a relapse. What do you think about the idea? I'm also considering hypnotherapy (I know a good professinal in my area), but I'm not really sure about it.

[bleep]

Fast Titration Schedule

Hi Sober,

I'm finding indifference to not be a point that I reach, but a state of mind, and a function of dose. For me there is no titrating down. I'm not sure what you mean about the pure physical dependence problems, but lurking at 600mg's for the rest of your life doesn't really sound feasible.

What dose have you settled on as a maintenance dose?

I have not found prn doses to be effective, but some people have, so it certainly is worth trying. Have you tried at all in the past?

Here's a thought - document when you have your relapse. You may find it occurs with regularity x number of days apart. If that is indeed the case, perhaps you can just up your dose when the danger period looms. It's unlikely to be so clean cut, but perhaps something along those lines?

As regards the hypnotherapy - why not. Tiptronic would refer you to the toolbox elsewhere on the forum, have you had a look through that? Personally, it's not my scene, but if you could find something to employ and prevent these one-off benders, it sounds like you'll be sorted.

[bleep]

Fast Titration Schedule

Sober, I also remember reading somewhere (probably in something you posted!) that taking large amounts of baclofen in one go affects the absorption in a negative way. I'll try find the article.

Just something to think about when taking 150 in one go - it may be better to take it 40, 40, 40 ,30 twenty minutes apart, or some such thing.

[I-want-to-be-sober]

Fast Titration Schedule

Thanks for your response!

Absorption won't be negatively effected, peak plasma levels will be reached faster compared to splitting the 150mg apart, obviously. Of course I don't recommend taking such a huge dosage on an as needed basis for most people, especially when alcohol has been consumed too (altough the CNS depressing effect is just additive and not potentiated like with e.g. benzos).

What's your opinion on combining it with NTX? IMHO it can't hurt and probably helps with loss of control problems.