Hey Sassy, I'm pasting my reply to you on RedHead's thread here:
Don't want to hijack your thread, but thank you for asking...I'm at 250 right now. Biggest side effects that bother me: water weight gain/edema. MY FEET ARE ROUND!! This is just in the last week or 2. I've taken to wearing support hose to keep from having completely unidentifiable ankles! Haven't had any AF days, so that may be holding me up. Wanting, wishing, waiting
Hey sassy, I had nasty edema too for a while. So much so that I dropped a BP Med, norvasc (a calcium channel blocker that also causes edema) permanently. The edema was periodic from around 100-200 or so lasting for 10-14+ days at a time. It passed and has never returned post switch. Sorry redhead for continuing the hijack. Glad to hear that things are starting to shape up for you -tk
Lo0p;1112188 wrote: I can't help but think: Isn't peripheral edema a side effect of alcohol abuse? Isn't it a sign that this sh&t is getting serious?
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I believe baclofen affects electrolyte channels in some way. I don't understand the physiology well enough to make a hypothesis without more boning up on the biology. I do know that when my bac dose was cut from 235 to 80, my potassium level dropped (dangerously) for a few days and had to be supplemented. Baclofen *may* affect efficiency of renal clearance, but I can't find evidence any where of it damaging or dangerously overtaxing the kidneys. I'm guessing that it's something that the body has to get used to, and as I've said, I've had my episodes and they've completely resolved themselves (and a few other folks have mentioned it here as well).
And, Sassy, maybe you should watch your sodium intake?
Otherwise, I agree that you seem to be on track and well on your way. 250 is indeed high, and when I got there, I *really* started to think "oh fuck, I haven't reached my switch, I'm almost at 300!!!! What am I going to do???" When it happened at 280, I was completely surprised, totally shocked, didn't see it coming, and *KNEW* that it was real (and by that time reports of others going over 300 to reach there switch were surfacing anyway...so). Anyway, you go girl. -tk
p.s. did you mention an anti-depressant that you are taking?
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