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Half Life and Maximum Concentration of Baclofen

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    #16
    Half Life and Maximum Concentration of Baclofen

    Article posted by Terry over on Consolidated thread is relevant here. Particularly interesting is Fig 1. Interestingly they suggest the long elimination, extended half life may be due to renal dysfunction whereas the previous link I posted on this thread suggests it's due to CNS depression.


    terryk;1112161 wrote: ]
    Started Baclofen 3/9/10 Hit my switch at 250mg on 21/11/10 Present maintenance dose of 50mg : started drinking after 1 year, upped dose to 80mg and stopped: Tapered to 30mg, started 6 months of drinking, upped dose to 240mg to stop 12/7/12

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