Consolidated Baclofen Information Thread

[Lo0p]

*Under Construction*



Baclofen



Dr Olivier Ameisen?s website:
? Olivier Ameisen, MD

His books:
? Macmillan: End of My Addiction: Books: Olivier Ameisen, M.D.
? 'Heal Thyself: A Doctor at the Peak of His Medical Career, Destroyed by Alcohol--and the Personal Miracle That Brought Him Back' by Olivier Ameisen (Dec 2009)

Wikipedia entry:
? Baclofen - Wikipedia, the free encyclopedia

An interview with Dr. Ameisen, the first doctor in this news clip, Dr James Garbutt, is a researcher that did a study with alcoholic patients and low dose baclofen (3x10mg/day). He found that it was effective, but not completely successful. Dr. Ameisen lost all craving for alcohol when he reached a dose of 270mg/day, nine times the dose used In the study. He continues to take 50mg/day now, five years later:
? A Cure for Alcoholism? - ABC News

YouTube video of PET scan showing reduced cocaine craving in the brain:
? http://www.youtube.com/watch?v=byain0Vo5mo[/video]]YouTube - Baclofen dramatically reduces cocaine craving

? Suppression de la dependance a l?alcool et de la consommation
d?alcool par le baclofene a haute dose : un essai en ouvert
Annales Medico-Psychologiques 168 (2010) 159?162
(PDF)(French)(Look at me being all linguocentric:sigh

? CASE REPORT
COMPLETE AND PROLONGED SUPPRESSION OF SYMPTOMS AND CONSEQUENCES OF ALCOHOL-DEPENDENCE USING HIGH-DOSE BACLOFEN: A SELF-CASE REPORT OF A PHYSICIAN
OLIVIER AMEISEN
Alcohol & Alcoholism Vol. 40, No. 2, pp. 147?150, 2005
(PDF)

? BACLOFEN EFFICACY IN REDUCING ALCOHOL CRAVING AND INTAKE: A PRELIMINARY DOUBLE-BLIND RANDOMIZED CONTROLLED STUDY
Alcohol and Alcoholism Vol. 37, No. 5, pp. 504-508, 2002

? CASE REPORT: SUPPRESSION OF SYMPTOMS OF ALCOHOL DEPENDENCE AND CRAVING USING HIGH-DOSE BACLOFEN
WILLIAM BUCKNAM
Alcohol and Alcoholism 2007 42(2):158-160

? Baclofen: a new drug for the treatment of alcohol dependence
Int J Clin Pract, August 2006, 60, 8, 1003?1008
(PDF)

? Baclofen in the Treatment of Alcohol Withdrawal Syndrome: A Comparative Study vs Diazepam
The American Journal of Medicine
Volume 119, Issue 3, March 2006, Pages 276.e13-276.e18
(PDF)

? Baclofen suppresses motivation to consume alcohol in rats
Psychopharmacology (2003) 167:221?224
(PDF)

? Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study.
Lancet. 2007 Dec 8;370(9603):1915-22.
(PDF)

? Acute interaction of baclofen in combination with alcohol in heavy social drinkers.
Alcohol Clin Exp Res. 2009 Jan;33(1):19-30.
(PDF)

? Clinical and pharmacokinetic aspects of high dose oral baclofen therapy.
J Am Paraplegia Soc. 1992 Oct;15(4):211
J Am Paraplegia Soc. 1992 Oct;15(4):212
J Am Paraplegia Soc. 1992 Oct;15(4):213
J Am Paraplegia Soc. 1992 Oct;15(4):214
J Am Paraplegia Soc. 1992 Oct;15(4):215
J Am Paraplegia Soc. 1992 Oct;15(4):216

? High-dose oral baclofen: experience in patients with multiple sclerosis.
Neurology. 1991 Nov;41(11):1829
Neurology. 1991 Nov;41(11):1830
Neurology. 1991 Nov;41(11):1831

? Forums dedicated to the collection and spread of knowledge about baclofen for addiction
Home - Baclofen UK
Baclofen Forum
Le baclofene - Association AUBES
(French)

?


? Informative and educational threads on this forum complete with factual information, titration schedules and personal experiences:
https://www.mywayout.org/community/f2...ion-34919.html
https://www.mywayout.org/community/f2...ead-35166.html
https://www.mywayout.org/community/f2...ead-35995.html
https://www.mywayout.org/community/f2...fen-35375.html

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

Some other useful threads:

https://www.mywayout.org/community/f2...ead-48260.html


https://www.mywayout.org/community/f2...fen-35375.html


https://www.mywayout.org/community/f2...fen-47958.html

https://www.mywayout.org/community/f2...aclofen+thread

[tiptronic_ct]

Consolidated Baclofen Information Thread

Excellent - thank you

[Greg]

Consolidated Baclofen Information Thread

Brilliant work Lo0p!

[redhead77]

Consolidated Baclofen Information Thread

Two thumbs up!

[bleep]

Consolidated Baclofen Information Thread

Good stuff. Thanks Lo0p.

[ik1966]

Consolidated Baclofen Information Thread

great job.....
:goodjob:

i will print it out and sent it to my shrink.....
thanks....

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

I thought this and some other of the threads we refer to (or could!) regularly might have a place on here.

Ne/Neva Eva;1058734 wrote: I am not a physician and have no background/knowledge of medicine or medical issues.

This is the list from epocrates. They are mostly related to CNS suppression, or increased risk of somnolence (extreme tiredness) I think.
(If you have any questions you can sign up for a free trial anonymously. Or pm me and I'll look up something specific.)

Drug Interactions .
Avoid/Use Alternative

* sodium oxybate

Monitor/Modify Tx

* dexmedetomidine
* exenatide
* hypoglycemics, other
* insulins
* liraglutide
* saxagliptin
* saxagliptin/ metformin
* sitagliptin
* sulfonylureas
* thiazolidinediones

Caution Advised

* acetaminophen/ caffeine/ CNS depressant combos
* acetaminophen/ chlorpheniramine
* acetaminophen/ chlorpheniramine/ dextromethorphan
* acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine
* acetaminophen/ chlorpheniramine/ phenylephrine
* acetaminophen/ diphenhydramine
* acetaminophen/ diphenhydramine/ phenylephrine
* acetaminophen/ doxylamine/ dextromethorphan
* acetaminophen/ doxylamine/ dextromethorphan/ phenylephrine
* acetaminophen/ doxylamine/ dextromethorphan/ pseudoephedrine
* acetaminophen/ doxylamine/ phenylephrine
* acetaminophen/ pheniramine/ phenylephrine
* aldesleukin
* antidepressants, other
* antihistamine/ decongestant combos
* antihistamines, sedating
* antipsychotics
* apomorphine
* aspirin/ chlorpheniramine/ dextromethorphan
* aspirin/ chlorpheniramine/ dextromethorphan/ phenylephrine
* aspirin/ chlorpheniramine/ phenylephrine
* aspirin/ diphenhydramine
* aspirin/ doxylamine/ dextromethorphan/ phenylephrine
* azelastine nasal
* barbiturates
* botulinum toxins
* brompheniramine/ dextromethorphan/ phenylephrine
* brompheniramine/ dextromethorphan/ pseudoephedrine
* bupropion
* butalbital/ acetaminophen
* BZDs, all
* calendula
* cannabinoids
* capsicum
* carisoprodol/ aspirin
* central alpha 2 agonists
* cetirizine
* cetirizine/ pseudoephedrine
* chamomile, German
* chlordiazepoxide/ clidinium
* chlorpheniramine/ dextromethorphan
* chlorpheniramine/ dextromethorphan/ phenylephrine
* chlorpheniramine/ dextromethorphan/ pseudoephedrine
* chlorpheniramine/ hydrocodone
* CNS depressant/ aspirin/ caffeine combos
* dantrolene
* doxylamine/ dextromethorphan
* droperidol
* ethanol
* ethosuximide
* gabapentin
* ginseng, Siberian
* goldenseal
* gotu kola
* hawthorn
* hydrocodone/ ibuprofen
* kava
* lemon balm
* levocetirizine
* lindane topical
* melatonin
* meprobamate
* methadone
* metoclopramide
* mitotane
* morphine liposomal
* olanzapine/ fluoxetine
* olopatadine nasal
* opiate agonist/ antagonists
* opiate/ acetaminophen combos
* opiate/ aspirin combos
* opiates
* oxcarbazepine
* oxycodone/ ibuprofen
* passionflower
* pheniramine/ dextromethorphan/ phenylephrine
* phenobarbital/ hyoscyamine/ atropine/ scopolamine
* phenothiazines
* pimozide
* pramipexole
* pregabalin
* promethazine/ codeine
* propofol
* propoxyphene
* propoxyphene/ acetaminophen
* ropinirole
* rotigotine transdermal
* rufinamide
* sedative/ hypnotics
* sodium phosphate
* sodium sulfate/ potassium sulfate/ magnesium sulfate
* tapentadol
* tetrabenazine
* thalidomide
* tiagabine
* topiramate
* tramadol
* tramadol/ acetaminophen
* tricyclic antidepressants
* valerian
* valproic acid derivatives
* vigabatrin
* ziconotide intrathecal
* zonisamide

Murphyx;1158533 wrote: RE the list of drug interactions 2 posts up: can I just point out to our Brit viewers that acetaminophen is known to us as Paracetamol.

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

An old article, and a dated one, but very interesting nevertheless. Dr. Childress at UPenn has since followed up with more research on addiction and baclofen.

Genetic Studies Promise a Path to Better Treatment of Addictions

[Murphyx]

Consolidated Baclofen Information Thread

RE the list of drug interactions 2 posts up: can I just point out to our Brit viewers that acetaminophen is known to us as Paracetamol.

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

Baclofen related articles:

http://dl.dropbox.com/u/15371700/Sci...serink-653.pdf

A Prescription Muscle Relaxer May Be The Wonder Cure For Alcoholism - Worldcrunch - All News is Global

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

Words from Dr. Olivier Ameisen:

https://www.mywayout.org/community/f2...sen-41374.html

https://www.mywayout.org/community/f2...sen-41375.html

https://www.mywayout.org/community/f2...age-41376.html

https://www.mywayout.org/community/f2...age-41377.html

https://www.mywayout.org/community/f2...you-52224.html

[Lo0p]

Consolidated Baclofen Information Thread

Thanks, everyone!

Thank you all for your contributions. I should edit all of this into the original post. If someone would show me, or rather, take up the responsibility of housing all of this information on a website that more than one person has control of, then it would be updated faster and could be edited by more than someone like me. I don't feel comfortable with deciding alone what should go up there.

And then it won't be subject to our often risque avatars.

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

Can't help you with that one, Lo0p.

A study done in Glasgow:

http://www.rcpsych.ac.uk/pdf/Baclofe...0Masson_A0.pdf

[Ne/Neva Eva]

Consolidated Baclofen Information Thread

Information related to Dr. Levin:
https://www.mywayout.org/community/f2...sen-41531.html
Information about finding a doctor:
https://www.mywayout.org/community/f2...ion-47247.html