I recently re-read the Wikipedia (I know, great source of information) entry on Oxytocin.
Oxytocin - Wikipedia, the free encyclopedia
In it, that I somehow missed the first time around are the following quotes:
"According to some studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs (opiates, cocaine, alcohol) and reduces withdrawal symptoms." Does this sound familiar to anyone?
"Sexual arousal. Oxytocin injected into the cerebrospinal fluid causes spontaneous erections in rats,[34] reflecting actions in the hypothalamus and spinal cord." Uncontrolled horniness abounds in the baclofen threads!
"MDMA (ecstasy) may increase feelings of love, empathy and connection to others by stimulating oxytocin activity via activation of serotonin 5-HT1A receptors, if initial studies in animals apply to humans.[53] The anxiolytic Buspar (buspirone) also appears to produce some or all of its effect via 5-HT1A receptor-induced oxytocin stimulation." Several people have reported this feeling.
"Bonding. In the Prairie Vole, oxytocin released into the brain of the female during sexual activity is important for forming a monogamous pair bond with her sexual partner. Vasopressin appears to have a similar effect in males.[46] Oxytocin has a role in social behaviors in many species, and so it seems likely that it also does in humans. In 2003, a study showed that in both humans and dogs oxytocin levels in the blood rose after five to twenty four minutes of a petting session. It is possible that this plays a role in the emotional bonding between humans and dogs." This at least goes part way to explaining the excessive love for pets that some people have. Murph, it's not your fault you like sheep. Like all things, it's chemical in nature.
There are many more relevant quotes, have a read, it's fascinating. It seems many of the SE's are attributable to this hormone, well, the good ones anyway. Among the SE's are the following:
"Decreased heart rate or heart rate decelerations"
Which quite a few people have reported.
and
Nausea and vomiting
Which has also been reported.
Sadly, death is among them as well, but clearly that's not an issue here.
The problem seems to be in the very short half-life (3 minutes), but I suppose if you ran around all day feeling like you were on E, you'd not get much productive stuff done. That happened to me though for a few days, and other people have reported it lasting for a while.
Very interesting stuff indeed.
Oxytocin - Wikipedia, the free encyclopedia
In it, that I somehow missed the first time around are the following quotes:
"According to some studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs (opiates, cocaine, alcohol) and reduces withdrawal symptoms." Does this sound familiar to anyone?
"Sexual arousal. Oxytocin injected into the cerebrospinal fluid causes spontaneous erections in rats,[34] reflecting actions in the hypothalamus and spinal cord." Uncontrolled horniness abounds in the baclofen threads!
"MDMA (ecstasy) may increase feelings of love, empathy and connection to others by stimulating oxytocin activity via activation of serotonin 5-HT1A receptors, if initial studies in animals apply to humans.[53] The anxiolytic Buspar (buspirone) also appears to produce some or all of its effect via 5-HT1A receptor-induced oxytocin stimulation." Several people have reported this feeling.
"Bonding. In the Prairie Vole, oxytocin released into the brain of the female during sexual activity is important for forming a monogamous pair bond with her sexual partner. Vasopressin appears to have a similar effect in males.[46] Oxytocin has a role in social behaviors in many species, and so it seems likely that it also does in humans. In 2003, a study showed that in both humans and dogs oxytocin levels in the blood rose after five to twenty four minutes of a petting session. It is possible that this plays a role in the emotional bonding between humans and dogs." This at least goes part way to explaining the excessive love for pets that some people have. Murph, it's not your fault you like sheep. Like all things, it's chemical in nature.
There are many more relevant quotes, have a read, it's fascinating. It seems many of the SE's are attributable to this hormone, well, the good ones anyway. Among the SE's are the following:
"Decreased heart rate or heart rate decelerations"
Which quite a few people have reported.
and
Nausea and vomiting
Which has also been reported.
Sadly, death is among them as well, but clearly that's not an issue here.
The problem seems to be in the very short half-life (3 minutes), but I suppose if you ran around all day feeling like you were on E, you'd not get much productive stuff done. That happened to me though for a few days, and other people have reported it lasting for a while.
Very interesting stuff indeed.
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