No more baclofen for me
What does it say about Eastern Europeans, B?
What does it say about Eastern Europeans, B?
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Knowledge of what is possible is the beginning of happiness.
George Santayana -
No more baclofen for me
Hmmm indeed! I was going to first use diabetes as an example. Type ones still need different types of insulins and type twos need all different drugs. I decided not to go with diabetes because it is only related to the pancreas. I feel diseases involving neurobiologyNe/Neva Eva;1157227 wrote: hmmm. What about, just for the sake of discussion, if a more apt comparison for alcoholism is diabetes rather than say, depression. Interesting thought, isn't it? A little genetics, a little epigenetics, a little trauma or drama... oy, the options are endless, aren't they?
Point is, maybe, that there could in fact be a medicine that takes care of the ... chemical imbalance(?). I'm not for a moment suggesting that it's one we know about. I am suggesting that the disease of alcoholism might be aptly compared to something physical and treatable, like diabetes, rather than ephemeral and misunderstood, like depression. And that even (or especially) in the case of diabetes, behavioral changes go a long way toward long term success. Right?
Fun stuff to think about. For me anyway.
are much more difficult to break down. Diabetes breaks down to how much or little insulin is secreted by the pancreas, and how well the insulin works to get the sugar into our cells. Researchers know the exact process and where and how it can go wrong. Not so with diseases involving neurotransmitters and how our life experiences affect our neurotransmitters.
It is food for thought, Ne.This Princess Saved HerselfComment
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No more baclofen for me
Pete, I don't think it breaks that group out. American Indians, Asians, celts are the ones I recall. I don't know where the book is, but I'll look it up when I find it. I think Depression Free Naturally has this info too if anyone has that and can post from it.
Just recalled the Wall Street Journal had an article about "who gets drunk and why." It says many Asians have a genetic variation that gives them a flush and a very rapid heartbeat from even a small amount of alcohol .... (reading) .... men vs women ... big person vs small person, empty stomach vs full, fatigue/stress makes it easier to get drunk. What caught my eye was this "How does BAC work" which of course made me think of baclofen. But alas no. BAC = blood alcohol level in this article. Also says alcohol metabolism increases about ten percent right after ovulation.
Nothing we don't already know except it was news to me you can buy a $5.00 breathalizer on a key chain. That could be handy just in case you are questioning yourself before getting in the car.Comment
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No more baclofen for me
oy. Thanks, RedH. I wish I had an inkling of the understanding you have about this.redhead77;1157242 wrote: Hmmm indeed! I was going to first use diabetes as an example. Type ones still need different types of insulins and type twos need all different drugs. I decided not to go with diabetes because it is only related to the pancreas. I feel diseases involving neurobiology are much more difficult to break down. Diabetes breaks down to how much or little insulin is secreted by the pancreas, and how well the insulin works to get the sugar into our cells. Researchers know the exact process and where and how it can go wrong. Not so with diseases involving neurotransmitters and how our life experiences affect our neurotransmitters.
Your response brings to mind a thread we had a while back about the amygdala/brain/alcoholism. I was intent on finding THE answer to it all. Only after much time and effort did I realize that people who didn't need to use google to look up the big words had spent their adult lives trying to figure it out...
Damn neurobiology. Very interesting stuff, though.
xoComment
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No more baclofen for me
Very interesting. I had never thought about ancestors and their diet and our "diet" today. Thanks Hilde =)Bruunhilde;1157213 wrote: Ne, I've experienced that drip and the symptoms of a bad cold that bac brings, as have many. Its real.
Redhead, I agree there are many types of alcoholics, or at least a few. Seven Weeks to Sobriety categories based on genetic pool, and has very good reasoning. For example, if you're celtic, you need Omega 3 oils because your ancestors evolved on a diet high in fish and you are likely deficient. If you're Asian, you may not be able to metabolise alcohol. Etc. For each type, there is a slightly different list of supplement to help the type recover, heal, gain control over the addiction.Still fighting the good fight.
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No more baclofen for me
I haven't experienced any drip that I am aware of. However, there have been times in the morning, when I just woke up, when I have felt like I was choking. =(Still fighting the good fight.Comment
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No more baclofen for me
Thanks Bleep! =)bleep;1157158 wrote: Nobody ever thought you were nuts, at least I didn't. I had it too. Thanks for the link, it's one I haven't come across before.
Glad to hear that a low dose is proving effective, and that you're winning!Still fighting the good fight.Comment
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No more baclofen for me
NE, I am taking 60mg a day. Thought recently I have slacked and taken 40mg. I am going back up to 60mg's because I have noticed a negative difference in my thinking while taking 40mg's. I am much happier at 60mg's. The cough has lessen compared to when I was taking 90mg's. At this point, I don't mind being on baclofen. The cough is troublesome but tolerable, especially now that I know WHY I have this cough. lol I assumed as much but wasn't sure until I came across the information that I found. The way I read it was that those patients were healthy and developed a cough while taking baclofen. Murph read it the other way. Perhaps I am wrong??? I just googled baclofen cough and that was the first article that appeared. =)Ne/Neva Eva;1157180 wrote: Which is really fascinating. Glad we got the article.
DandT, Baclofen does, in fact, cause nasal congestion. It also causes post-nasal drip. These side effects can be found on the information given to you at the pharmacy.
From Wiki:
Post-nasal drip (PND), also known as Upper Airway Cough Syndrome (UACS), occurs when excessive mucus is produced by the nasal mucosa. The excess mucus accumulates in the throat or back of the nose. It can be caused by rhinitis (allergic or non-allergic), sinusitis (acute or chronic), laryngopharyngeal acid reflux (with or without heartburn), or by a disorder of swallowing (such as an esophageal motility disorder). It is frequently caused by allergies, which may be seasonal or persistent through the year.
(of course, and to the point, it is caused by baclofen as well as the other things.)
If you take an allergy medicine, or a benadryl, it will stop. Today.
I'm not being snarky, though I am being a little bit impatient.
If you need baclofen to help you stop drinking, and you are using the services of a physician, and you are committed to finding a solution to your alcoholism, then it is really wise to use the tools you have to get the job done.
I'm very glad that you have found some clarity. I suspect you are taking the doses at regular intervals and consistently. If that is not the case, would you let me know? I'm simply curious. This is often not the case with people who are having issues at lower doses.
Take good care, DandT. It's an important struggle your facing.Still fighting the good fight.Comment
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No more baclofen for me
Murph, I reread the article, and you are correct. What puzzles me though is why they would do a study on "healthy" people in regards to a cough. How can one be "healthy" with a cough? lolMurphyx;1157161 wrote: That study shows the opposite. Baclofen stops coughs, it doesn't cause them.
Either way, I have read other information in regards to animals having coughing while taking baclofen.Still fighting the good fight.Comment
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No more baclofen for me
DandT, capsaicin is pepper. The people were smelling pepper and then coughing. The researchers gave them baclofen in order to study whether or not baclofen reduced the coughing reaction. It's what researchers do.
Their conclusions:
These results confirm the recent observation that baclofen has significant antitussive activity in humans. (antitussive means cough suppressing)
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These results support further investigation of baclofen or other GABA-agonists as potential therapeutic agents for chronic, nonproductive cough.
This means that baclofen actually helps reduce coughing. I point this out because I want to be completely clear that baclofen is not causing your cough. It is very likely that baclofen is reducing your coughing, which is being caused by something else.
It might be a good idea to find out what that something else is. Or not. If it's getting better than it's not an issue any more, and I'm glad.
I'm also glad that you seem to have found a level that works for you. I also found bac to be helpful with my negative thought merry-go-round. I haven't found a study about that, yet! I'm sure someone around here has, though.
The article was interesting for other reasons, too. Thank you again for pointing it out. (Gaba in the lungs? Who knew? Not me for sure...)Comment
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No more baclofen for me
Well I don'y know what is making me cough. I didn't start until I started taking baclofen. lol The higher the dose the worse the cough. Since lowering my dose, my cough has lessened. I can only conclude that it IS in fact he baclofen. I read somewhere that it does effect something in the brain that has to do with your respiratory system. I can't remember where I read that though. I will make an appointment with the doctor as soon as I have the money. It would be great to talk to a neurologist about baclofen. As other people have stated on here, my coughing while taking baclofen is not uncommon. I will keep you all posted once I speak to a doctor. =)Ne/Neva Eva;1160464 wrote: DandT, capsaicin is pepper. The people were smelling pepper and then coughing. The researchers gave them baclofen in order to study whether or not baclofen reduced the coughing reaction. It's what researchers do.
Their conclusions:
These results confirm the recent observation that baclofen has significant antitussive activity in humans. (antitussive means cough suppressing)
...
These results support further investigation of baclofen or other GABA-agonists as potential therapeutic agents for chronic, nonproductive cough.
This means that baclofen actually helps reduce coughing. I point this out because I want to be completely clear that baclofen is not causing your cough. It is very likely that baclofen is reducing your coughing, which is being caused by something else.
It might be a good idea to find out what that something else is. Or not. If it's getting better than it's not an issue any more, and I'm glad.
I'm also glad that you seem to have found a level that works for you. I also found bac to be helpful with my negative thought merry-go-round. I haven't found a study about that, yet! I'm sure someone around here has, though.
The article was interesting for other reasons, too. Thank you again for pointing it out. (Gaba in the lungs? Who knew? Not me for sure...)Still fighting the good fight.Comment
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No more baclofen for me
NE - You probably already know this but Wiki is NOT a credible source.Ne/Neva Eva;1157180 wrote: Which is really fascinating. Glad we got the article.
DandT, Baclofen does, in fact, cause nasal congestion. It also causes post-nasal drip. These side effects can be found on the information given to you at the pharmacy.
From Wiki:
Post-nasal drip (PND), also known as Upper Airway Cough Syndrome (UACS), occurs when excessive mucus is produced by the nasal mucosa. The excess mucus accumulates in the throat or back of the nose. It can be caused by rhinitis (allergic or non-allergic), sinusitis (acute or chronic), laryngopharyngeal acid reflux (with or without heartburn), or by a disorder of swallowing (such as an esophageal motility disorder). It is frequently caused by allergies, which may be seasonal or persistent through the year.
(of course, and to the point, it is caused by baclofen as well as the other things.)
If you take an allergy medicine, or a benadryl, it will stop. Today.
I'm not being snarky, though I am being a little bit impatient.
If you need baclofen to help you stop drinking, and you are using the services of a physician, and you are committed to finding a solution to your alcoholism, then it is really wise to use the tools you have to get the job done.
I'm very glad that you have found some clarity. I suspect you are taking the doses at regular intervals and consistently. If that is not the case, would you let me know? I'm simply curious. This is often not the case with people who are having issues at lower doses.
Take good care, DandT. It's an important struggle your facing.
Still fighting the good fight.Comment
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No more baclofen for me
Bleep, how long did your cough last?bleep;1157158 wrote: Nobody ever thought you were nuts, at least I didn't. I had it too. Thanks for the link, it's one I haven't come across before.
Glad to hear that a low dose is proving effective, and that you're winning!Still fighting the good fight.Comment
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No more baclofen for me
A couple of weeks.Comment
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No more baclofen for me
I thought it just dried your throat out, and that's what made you cough.Comment
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