I am getting annoyed by this. I also blame OA for what I consider to be bad advice in his book and I blame him and others who do not understand this point for a lot of what we have had happen to us
OA suggests that you have to go up to a dose dependent on body weight. He also says that he took it in three doses of 60, 30 and 60. That is all I could get from his book. First, I think it is very sparse detail when considering such an important treatment and in light of the massive interest in the treatment and the desperation of those needing it. It leaves no guidance on how to take it.
So, suppose the total dose right for you is 270 mg per day. What does that mean, just on its own. Nothing. It is even potentially harmful advice. Suppose you took the whole 270 at once. You would sky rocket up, have massive SE's and then plummet down. Is that how stable brain chemistry works? And, as you plummet down again do you reach for a bottle?
The same goes if you divide it into three doses of 90 mg. Or do you take nine doses of 30 mg or 27 doses of 10 mg?
The answer is that the dosage depends not on body weight as suggested by OA, but on liver metabolism. You have to find out what level of Baclofen in your system stops craving but does not cause SE's. So, if you have to take 240 per day in 6 divided doses every 4 hours, what that means is the correct level for you is 40 mg in your system, not 240. If you have to take your doses every 4 hours, then that is the elimination rate. If you liver eliminates that amount every 5 hours then you need to take less in total per day.
One person may need 25 mg every 3 hours, another might need 30 mg every 2 hours. That is what determines total daily dose.
That is what I mean when I say that the total daily dose is not important. It is about keeping a level amount in your system and that depends on your own elimination rate and experimenting to find out what dosage gives you relieve from craving without side effects.
This lack of information means that some have taken large individual doses and find the treatment has too many side effects and just does not work. Then, because of the SE's some decide not to take it, go off it, return to drinking, mixing drink with Baclofen and get themselves into hellish problems. Until they find someone who understands this.
I hope I have made myself clear.
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