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    Something I Found Interesting...

    Hey all!
    This was posted in my SMART Recovery's Google group, and I found it promising. I didn't do any background research into it, so please don't hold me accountable if it turns out to be nonsense.

    Easing Addiction Memories

    By ALBERT NERENBERG, Special to The Gazette November 19, 2011


    Researchers Dr. Alain Brunet (left) and Michelle Lonergan are looking at using PTSD treatment that ?dampens? memories to help drug addicts.
    Photograph by: Allen McInnis, The Gazette
    MONTREAL - The urge to satisfy an addiction is said to be one of the most powerful cravings known to man. Addict‟s brains wire around burning desires that override reason, and even family. The clich? that someone would sell their own grandmother is not actually a clich?. Many addicts have stolen from their own grandmothers and worse.

    What‟s amazing to me as someone who has worked in a rehab centre is this: Take people off their substance and, after detox, they quickly become upstanding citizens ? considerate, responsible and good-natured. Put them back on the drugs or alcohol and the madness begins anew.

    It‟s clear to me addiction is not a moral quality but more a neurochemical one, probably capable of distorting just about anyone. Actor Gary Busey once famously snorted cocaine off his dog, which had rolled in the drug after Busey dropped it on the floor. Keith Richards snorted his dead father‟s ashes mixed with cocaine. Whitney Houston demolished a fabulous life with addiction. Worse still, many addictive personalities, like late singer Amy Winehouse move toward a terminal finale.

    But solving addiction is one of the most intractable issues in science, with many addicts doomed to cycles of relapse. The CBC‟s Nature of Things reported on Nov. 10 that traditional Canadian rehab programs have a success rate of only eight per cent. But a research project initiated in Quebec may offer something new. Montreal‟s Douglas Hospital in association with McGill University is currently recruiting test subjects for a pilot approach to treating addiction based on a successful treatment for post-traumatic stress disorder.

    But aren‟t PTSD and addiction two completely different things? Sure. But they have one thing in common ? they‟re both driven by powerful memories. And scientists now say they can get into your brain and alter those memories. PTSD, traditionally known as shell shock, is an often-debilitating condition related to trauma usually caused by having experienced or witnessed violence, atrocities or abuse. PTSD sufferers can be haunted and crippled by the intense emotions triggered by a trauma that may be many years behind them. But there is now be a way to ?dampen? the charge of once potent PTSD memories. And it‟s possible scientists might be able to do the same thing with the powerful triggers that drive addiction.

    ?The reason we think that people suffer from addiction is because of cravings,? said McGill psychologist Alain Brunet, one of the world‟s leading trauma researchers who heads the project. ?A craving is a form of emotional memory ? it‟s a fond memory, but it‟s a memory that‟s very strong. But once things around you remind you of your drug use it triggers your cravings, and you very much want to use. What we found a few years ago that emotional memories, be they positive or negative, can be turned down or dampened.?

    Brunet, along with a team at Harvard and McGill Universities, developed a revolutionary way to treat PTSD lauded as one of Quebec Science magazine‟s Top 10 Scientific Discoveries of 2008. Brunet‟s work is based on the ?memory consolidation theory,? which identified a peculiar aspect of human memory. When a powerful memory is remembered, it also has to be packed away or re-consolidated into the brain. During that process there is a short time frame when that memory, even a potent habitual one, is vulnerable and malleable. With proper timing, powerful unhealthy brain patterns, even habits, could be disrupted.

    While PTSD is itself a factor in addiction, Brunet‟s pilot project focuses on the cravings in addiction, because, he says, the pilot project must focus on a single variable.

    Brunet‟s PTSD treatment, the subject of international publicity, is deceptively simple ? in effect, treating PTSD with a pill. The process goes like this: The subjects are asked to write the troubling memory down on a small piece of paper. One such story might read:

    ?He held the gun against my head. I heard my heart beating. I thought I was going to die.?

    Test patients are given a pill containing propranolol. Propranolol is actually a mild blood pressure drug, which happens to have an extraordinary effect on memories active while the drug is in the subject‟s system ? it dampens or de-intensifies them.

    The subject then holds up the paper with the memory on it and reads the difficult sentences five times. Why five times?

    ?It was just an educated guess,? said Brunet. But the act of going over a difficult, troubling memory, saying it out loud, has a measurable and surprising effect. It brings the memory back to life inside the brain, something science can actually see with brain scans. The person‟s heart starts to beat, sometimes their eyes tear up. At this moment, the troubling memory is hot and vulnerable.

    ?Propranolol will target the memories that will be activated while it‟s in the system,? said Brunet. ?The drug deadens that memory.?

    Any memories coming alive during the few hours that the drug is active are likely to be ?dampened.?

    ?You don‟t want to think about your wedding day,? said Brunet. ?I‟m saying this half-jokingly.?

    Only half, as the procedure might dampen any memory that becomes hot during the process, including happy ones. But Brunet believes the process is harmless because only memories systematically targeted over several weeks are affected.

    Using the process, PTSD sufferers have reported uncanny change. A memory of a shocking trauma seems to deflate and lose its power. It doesn‟t disappear, but becomes a distant memory like so many others.

    The parallel to addiction is intriguing. In both scenarios, people are victims of the powerful effect of memory essentially gone amok. Because they often represent lethal danger, our brains make PTSD memories impossible to forget and when triggered, these memories can push people into states of panic and anxiety. Similarly, the brain is convinced that addictive cravings are necessary and tied to relieving powerful anxieties, and won‟t let them go.

    Instead of writing down their traumas, the addicts isolate and write down the core memory that drives them to reach for the substance.

    Most addicts will usually describe a specific trigger or feeling. Here are the first few lines of one addict‟s story:

    ?It‟s Friday morning. I wake up feeling depressed, lethargic, and tense all over. All I can think is ?I would feel so much better if I had some coke.‟ I make plans with my friends for drinks after work; an excuse to use. It‟s all I can think of during my work day. As soon as I get home, I call my dealer, and wait for him to arrive. The anticipation of his arrival is overwhelming.?

    The addict also gets a pill, a dose of propranolol, and about 75 minutes later, the story is also read five times. After several sessions and a few weeks, the hope is that the powerful memory of using becomes a trivial distant memory.

    It‟s tempting to see this treatment as wishful thinking. Are addicts really driven by one single memory? Maybe. Although an addict could have multiple triggers or reminders of their use, ?they may all be variations on a theme,? says Brunet.

    Could the treatment destroy valuable parts of a person‟s memory?

    ?My answer is no,? said Brunet. ?Memories never disappear, their effective force can be reduced. We‟ve been doing the PTSD memory work since 2004, we‟ve never heard anyone say, ?Doctor I‟ve forgotten something important to me.‟ ?

    According to Brunet, most memories ?are generally not active but a few carry a huge, powerful emotional charge.? If those memories are controlling someone, dampening them might actually have a natural, healthy effect. A person who was hit by car shouldn‟t spend the rest of their lives being unable to cross a street. A person who enjoyed a glass of wine, shouldn‟t be destined to to never put a bottle down.

    Brunet doesn‟t yet see this treatment as a cure by itself.

    ?This is an adjunct to treatment currently,? he said, meaning addicts should be still be getting counselling and therapy while undergoing this experiment.

    Catherine Cosgrove, who runs the Heritage Home treatment centre in Huntingdon, is enthusiastic that the approach might evolve into a full, effective treatment. Cosgrove, a psychotherapist specializing in addiction, was instrumental in helping to get the Douglas pilot project off the ground by suggesting to Brunet his treatment could be applied to addiction. She says she was motivated by the high relapse rate among addicts, and a sense that there has to be a better way.

    Cosgrove believes the new approach could be used at both ends of addiction.

    ?The new research is really suggesting what makes addicts different form the rest of us is usually trauma,? she said. ?There really is a PTSD connection with addiction in that most addicts have some kind of recognized or unrecognized PTSD.?

    That PTSD, says Cosgrove, drives its victims to high states of anxiety, and that person eventually finds something to sedate them, sending them down the road to addiction.

    Cosgrove says the ultimate application of this approach is to use the method to dampen both PTSD as addiction‟s source and de-intensify the result of addiction, drug craving memories. Together, the new approaches could pack a memorable punch.
    "Yet someday this will have an end
    All choices made or choice resigned,
    And in your face the literal eye
    Trace little of your history,
    Nor ever piece the tale entire
    Of villages that had to burn
    And playgrounds of the will destroyed
    Before you could be safe from time
    And gather in your brow and air
    The stillness of antiquity."

    From "At Majority" by Adrienne Rich

    #2
    Something I Found Interesting...

    Interesting reading......
    IT'S NEVER TOO LATE TO BE WHAT YOU MIGHT HAVE BEEN
    Relapse starts long before the drink is drunk!!.Fresh Start!

    Comment


      #3
      Something I Found Interesting...

      Thanks for taking the time to post this Windycity:
      When I was 17 and had my first awful breakup coupled with lots of parental abuse , I kept thinking how great it would be to get a forget me pill and I wasn't thinking about alcohol.
      30 plus years later all those memories are just as painful I'm afraid. Maybe someone has finally created a forget me pill.
      On My Own Way Out Since May 20, 2012
      *If you think poorly of yourself, you can fail with a clear conscience.
      https://www.mywayout.org/community/f11/tool-box-27556.html tool box
      https://www.mywayout.org/community/f19/newbies-nest-30074.html newbie nest

      Comment


        #4
        Something I Found Interesting...

        Windy, this is great! Thank you for posting it.

        I've been thinking lately that I'm suffering from PTSD from a variety of experiences, and I've been watching myself drink to quell the anxiety that is constantly resurfacing as a result - even in spite of HDB. I can also trace my drinking back to the initial euphoria -and escape- that it gave me. How truly marvelous it is that there may be a way to tap into the brain's recollections and zap the most harmful of them with a little bit of chemical assistance. I, myself, would not fret over nullifying some of those memories! And I would take another chemical to quell the triggered nerves or whatever they are that make me behave as I have been, which only makes it all worse and prolonged.

        Good stuff!

        Comment


          #5
          Something I Found Interesting...

          Interesting article windy thanks for putting it on here. Propranolol is a beta blocker that is also used for anxiety and panic attacks. I cant take it tho because of having Asthma.

          Comment


            #6
            Something I Found Interesting...

            Sounds like a good back-up plan for me, well I could try it anyway. I have propranolol, but never would have dreamed it could be used for this purpose. It will be a valuable tool if it can work this way!

            Comment


              #7
              Something I Found Interesting...

              This might be totally random and off-topic, but since we're talking about memory I thought I'd mention it. I'm about halfway through this book called Moonwalking with Einstein (which I recommend regardless, it's pretty neat) about memory.

              Specifically, it's about the small number of people who memorize things competitively, like they spend an hour memorizing the order of 10 shuffled decks of cards. Then they see who remembers the order more completely. Anyway, there's a trick to it. Let's say you need to memorize a shopping list, and there's cottage cheese on the list. You imagine a place you're intimately familiar with, like your childhood home, and as you walk through the house you "place" reminders for the things on the list. So, walking up to the front door I'd place a giant tub of cottage cheese in the driveway, with Taylor Swift, wearing a bikini, sitting in the cottage cheese as though it were a hot tub, drinking champagne. I will never, ever forget that I need to pick up cottage cheese at the grocery store. (Though I'd probably have a nagging feeling I need to pick up champagne, too. )

              Where this becomes relevant to our discussion here is that I just got to the part where these guys need to forget a lot of stuff after a competition. They need to clear out space in their childhood home for the next competition--so they walk through it and "throw" things out. No idea how to do that yet--maybe help Taylor out of the cottage cheese, hand her a towel, and send her on her way?

              Anyway, if nothing else I hope this was interesting.

              Comment


                #8
                Something I Found Interesting...

                I'm glad you guys thought it was interesting too. Yes, Space, it is also used for anxiety and panic attacks, which is interesting unto itself. I'm volunteering to be our resident guinea pig. It's relatively cheap online, and my cousin who is a nurse has offered to oversee me do it. I did do more research into exact dosages and timing. It seems what's preferable is to take one dose of short acting propanolol followed by a dose of long acting propanolol. I don't know if I'll be able to find both, but we'll see. Someone else on the SMART google group said it was given to him years ago for PTSD and worked wonders.
                Doing more research unveiled how controversial these applications are, not from a safety point of view, but an ethical one. Some people have compared it to the drug in "Eternal Sunshine of the Spotless Mind." Supporters contend that it doesn't erase memories, just "reconsolidates" them, removing any excess emotion associated with specific memories. They make the point that PTSD and addiction occur after healthy mental processes are corrupted. I like their example of someone who's been hit by a car. Your brain is going to want you to be very afraid of cars after that. When you become addicted to a substance, your brain believes that you need that substance to survive. But no one derserves to be afraid of cars for the rest of their lives, right? In my opinion, no one deserves to be afraid of devastating cravings either.
                Euphoric recall has always been my downfall in sobriety. I have always been haunted by very pleasant memories of using, very specific scripts. There's no arguing with these memories. The best I can do is try to remind myself that even if these situations were initially pleasant, they don't end that way. But how amazing would it be to dampen these memories? Take away their "sexiness", if you will.
                I'm excited!
                "Yet someday this will have an end
                All choices made or choice resigned,
                And in your face the literal eye
                Trace little of your history,
                Nor ever piece the tale entire
                Of villages that had to burn
                And playgrounds of the will destroyed
                Before you could be safe from time
                And gather in your brow and air
                The stillness of antiquity."

                From "At Majority" by Adrienne Rich

                Comment


                  #9
                  Something I Found Interesting...

                  Stuck, we x posted. The nature of memory and memorization has always been fascinating to me. This is an awesome idea! I'd like to pick up the book.
                  Now that I've gotten sober, I'm realizing how much I don't remember of my past. It's not like I was in a blackout for my whole life. Alcoholic drinking actually interferes with the process of making new memories and can destroy existing ones as well. It's a very disconcerting feeling, feeling like you don't know exactly who you are. I remember reading a long time ago "a personality is many different selves knit together by memory." Who are we if we don't know what those selves were?
                  "Yet someday this will have an end
                  All choices made or choice resigned,
                  And in your face the literal eye
                  Trace little of your history,
                  Nor ever piece the tale entire
                  Of villages that had to burn
                  And playgrounds of the will destroyed
                  Before you could be safe from time
                  And gather in your brow and air
                  The stillness of antiquity."

                  From "At Majority" by Adrienne Rich

                  Comment


                    #10
                    Something I Found Interesting...

                    And I'm pretty sure I'll never forget to buy cottage cheese again either. And I don't even eat cottage cheese!
                    "Yet someday this will have an end
                    All choices made or choice resigned,
                    And in your face the literal eye
                    Trace little of your history,
                    Nor ever piece the tale entire
                    Of villages that had to burn
                    And playgrounds of the will destroyed
                    Before you could be safe from time
                    And gather in your brow and air
                    The stillness of antiquity."

                    From "At Majority" by Adrienne Rich

                    Comment


                      #11
                      Something I Found Interesting...

                      This was a great post! Definitely weighs in for me to be valuable information. I would be a resident guinea pig too, if it were available. Thank you so much for sharing this.
                      Enlightened by MWO

                      Comment


                        #12
                        Something I Found Interesting...

                        Windy is this therapy like Eye Movement Desensitization and Reprocessing, or EMDR only with a drug?

                        I have done some EMDR sessions. They were helpful. I would have continued but they were expensive. I also found that 'saying' some of those memories aloud was just more than I could bare.


                        :l
                        On My Own Way Out Since May 20, 2012
                        *If you think poorly of yourself, you can fail with a clear conscience.
                        https://www.mywayout.org/community/f11/tool-box-27556.html tool box
                        https://www.mywayout.org/community/f19/newbies-nest-30074.html newbie nest

                        Comment


                          #13
                          Something I Found Interesting...

                          Bigamy WINDY...
                          LOVE that you can say 'now that Ive gotten sober'!!!!

                          I would test this out too. May ask my Dr first biz I am on three blood pressure drugs already.
                          I love that this bo pill is used for panic attacks and anxiety and so der why a dozendoctors. Ive used over 30years of hypertension a d anxiety never thought of this for me. Why not replace one of my three pills with this? Maybe I have used Titus der a different trade name and couldn't handle the SEs...

                          Thanks for sharing this.

                          Comment


                            #14
                            Something I Found Interesting...

                            Windycitylady, I'm with you on remembering the cottage cheese, and I don't even like it, either! I just googled (how appropriate) "Moonwalking with Einstein" and can now hardly wait to read it...thanks, StuckinLA!
                            . "It is only with the heart that one can see clearly; that which is essential, is invisible to the eye.". Antoine de Saint-Exupery

                            Comment


                              #15
                              Something I Found Interesting...

                              Hey guys! I had an embarassing episode. I think I'm so used to the DIY culture around here that I thought nothing of posting on the SMART recovery google group page that I was going to try this by myself. The facillitator who posted it freaked out and sent me a private email begging me not to do it without a doctor's supervision, etc. And I felt silly. BUT turns out someone at the hospital that's doing the studies is somehow affiliated with SMART. He contacted her and told her of my interest. She emailed him back saying they were looking for participants and that I should contact them. She said that even if I couldn't participate in the study that the doctor mentioned in the article may be willing to instruct my doctor (who is nonexistent) in how to do it. The hospital is in Montreal, so I don't know if I could do it, not to mention that the other meds I take would probably disqualify me from participating in an actual research study. Nevertheless, I thought it was a very sweet and thoughtful thing for the SMART facillitator to do. And I probably will still contact them. (I'm secretly envisioning a trip to Montreal where I'm a guinea pig an hour a day and spend the rest of the time practicing French and visiting cathedrals. Of course, I'll probably meet my true love there too, a dashing Quebecois bastard son of Leonard Cohen.)
                              Bruun, the anti-anxiety stuff is interesting too. I've only read about people taking it on anxiety chat forums. I feel like they're normally taking it in conjunction with other anxiety meds. It stops the bodily symptoms of a panic attack, but not the brain symptoms. It would be strange to feel mentally terrified but physically calm...
                              "Yet someday this will have an end
                              All choices made or choice resigned,
                              And in your face the literal eye
                              Trace little of your history,
                              Nor ever piece the tale entire
                              Of villages that had to burn
                              And playgrounds of the will destroyed
                              Before you could be safe from time
                              And gather in your brow and air
                              The stillness of antiquity."

                              From "At Majority" by Adrienne Rich

                              Comment

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