High Dose Bac Not Neat And Easy

[Ne/Neva Eva]

High Dose Bac Not Neat And Easy

https://www.mywayout.org/community/f2...ess-64164.html

[MusiciansMallet]

High Dose Bac Not Neat And Easy

Ne/Neva Eva wrote: We don't know how/why/what bac does that the others don't (or maybe they do and bac doesn't.) And there isn't a financial incentive to figure it out (maybe) but, a BIG but! There are people that are looking into it in order to come up with something that they can actually make money from. (Not a bad thing, just expensive. They'll have 'incentive' programs, I'm sure. )
In the meantime, individual practitioners and even some traditional rehabs are getting on board. Albeit with desperate cases, it seems to me, but still. And the stuff works. And it's cheap. So even indigent-type patients can get it. Hell, they're most likely to get it so far anyway.

I don't really disagree w/ any of that. I was sharing my personal experience w/ taking TOO much baclofen too quickly for barbiturate dependency.

And yes; it is huge "but"- in regards to some--albeit very few here in the US--rehab centers, doctors, etc are jumping on board. Its not a patentable drug, so there's no where NEAR as many extensive studies done by pharmaceutical companies (via double-blind studies) as there is w/ say, huge money makers like suboxone for opiate/heroin/painkiller addiction. So, all we can really go on, so far, is awesome support forums like this; unless the drug is adopted widespread! And/or if some single-payer, national healthcare countries (in Europe, Canada, or Australia) decide to look into the drug more thoroughly (as a matter of public policy--since the private industry has much less of an interest due to less profit incentive)... by making double blind studies to determine its efficacy, interactions, effective doses, etc. Until then, SE & interactions are just anecdotal (be it through us or w/ Dr. A & others in the medical community who're usually marginalized)! We really don't know anything for sure about any sort of neurological interaction going on there w/ baclofen, aside from the fact that it is a GABA-B agonist (which, actually, theoretically shouldn't help w/ alcohol withdrawal SE's.. which confuses matters even more).

But, w/ all of that said- my recent experiences (as i've outlined in the thread i started) have definitely convinced me baclofen has some novel use in treating addiction/dependency on drugs/substances that act on GABA-A receptors (like alcohol in the OPers situation; & like my barbiturate medication in my situation). I'm noticing a huge decrease in craving & daily intake of butalbital (the medication i'm trying to get off, of course) w/ baclofen, even at really low doses of 15-20mg i've titrated up to (originally from 5mg!)

...ANYWAY, sorry, don't mean to derail this thread! Stay well Krill! Hope to see some of your updates! Be careful w/ high intakes of baclofen without slow titration upwards, first! although its a very short acting drug; I HIGHLY suspect there is some sort of other effect going on that causes adverse side effects some 2-3 days after initial high doses, in people w/o much tolerance to the drug (at least for me & in my experience! But this is also very commonly reported/documented on general-psychoactive drug-use (or harm reduction..) forums like Bluelight (Bluelight - The Front Page ); and on the website erowid (Erowid) which contains some "trip reports" (but it isn't a forum). BUT- take this w/ a grain of salt, usually these references/reports on baclofen use are w/ one-time high doses, w/ the user just trying to catch a buzz rather than to treat addiction/dependency)..