I really need help fast!

[redhead77]

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I'm glad you slept well, Keen. My understanding is within 48-72 hours the worst of it would set in.

[ifulovelife2]

I really need help fast!

Hey Keen

Sorry to hear you've had such a shitty time.

Are you sure what occurred was down to baclofen? It's just that you can't really overdose on baclofen by increasing your dose by 1/3 when you've been steady on it for 2 weeks.

I did get that right didn't I? You were on 300mg/d for 2 weeks, then took an extra 100mg and you think you overdosed? That's not enough for an overdose, not that there really is such a thing as a baclofen overdose.

Were you taking anything else at the time? Had you previously been and then stopped?

[ifulovelife2]

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keenegear89;1366722 wrote: My mom found me overdosing and took me to the er for vomit, double vision and not walking straight.
keenegear89;1366903 wrote: On Sunday I accidentally over dosed by taking 400mg instead of my 300mg and my mother find me twitching and drooling on the floor.

Keen, were you vomiting, suffering from double vision and not walking straight or were you actually on the floor twitching and drooling?

Also, how old are you and why were you taking baclofen in the first place?

Not relevant to your actual concern about withdrawal of course, but may well be to anyone who Googles baclofen withdrawal and finds your story.

Good luck!

[redhead77]

I really need help fast!

ifulovelife2;1367091 wrote: I did get that right didn't I? You were on 300mg/d for 2 weeks, then took an extra 100mg and you think you overdosed? That's not enough for an overdose, not that there really is such a thing as a baclofen overdose.

Hey Mx, that's not exactly true. There is such a thing as a baclofen overdose. People have ended up on ventilators when they have. Don't quote me because it's been some time since I've read the literature, but this usually happens when taking doses of like 700-1000 mg in one shot. People can have other symptoms of bac toxicity at even lower doses, though. However, I have to agree that it would be less likely when only taking a 100 extra.

[keenegear89]

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I am 23. I believe it was an overdose. I usually spread 100mg thru out the day. 100mg when I wake up, 100mg at 2pm and 100mg before bed. That day was stressful. I think I finished all my 300mg + the extra 100 by 5pm. I couldn't walk straight when I tried, I was vomiting, could not see straight, moving in weird ways. I just remember being very uncomfortable and laying down a lot. I kinda blacked out so I don't know everything. I was using baclofen because I am an alcoholic and get into a lot of legal problems. I've already had 3 dwi's and a bunch of other shit. It was weird that I did overdose because I am usually good at going up fast. Maybe it was because I was so stressed out that day. I did drink 3 beers also.

[COSGringo]

I really need help fast!

Way crazy. You can't go up and down like that. Please be careful. And benzos can help to get through it.

What you are doing is dangerous though if it's all true.

[keenegear89]

I really need help fast!

You guys definitely where not lying about the withdrawal! Holy freakin cow! I've been severely depressed all day so I went out to walk my dog and I've never been so paranoid in my life! My heart was pumping out of my chest! I am hearing stuff that is not there. I thought I had heard voices calling out for me but there was nobody. I snapped a tree twig and almost had a heart attack. I thought I'd be fine since I only took it for only 40 days but that's not the case it seems.

It took me 4 hours, 8 beers and 150mg just to calm down a bit. Hopefully I can get a little sleep tonight so I can work tomorrow.

Thank all of you for the info you provided to me. I am going to call the doc tomorrow. Thanks stuckin for the contact info! I'm kinda concerned he won't be able to write me the prescription because I just went into the ER for baclofen overdose but I'll find out tomorrow I guess.

[keenegear89]

I really need help fast!

Sorry I cant stop thinking. I'm still trying to figure out how I could have over dosed that day. I had switched from the inhouse brand (mylan) I think to rivers lioresal and I accidentally upped it that day to 400mg. I wonder if the river bac is more potent then the inhouses's brand. I know for one thing it sure seemed that way! Could that be why? Or they all about the same?

[Cashregister]

I really need help fast!

Didn't the hospital give you any info at all? Do you have a prescription drug info line you can call, or can you call the Ed and ask for advice?? I was on baclofen for a neurological reason - the upper limits for someone with say MS was 160mgs. Taper off but don't go back up high.

[Cashregister]

I really need help fast!

Ps different brands all have same amount of active ingredient they may just use different binding ingredients to make a pill. And you can overdose on any med if you take enough of it.

[Ne/Neva Eva]

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Cashregister;1367432 wrote: the upper limits for someone with say MS was 160mgs. Taper off but don't go back up high.
That's not accurate.

Cashregister;1367434 wrote: Ps different brands all have same amount of active ingredient they may just use different binding ingredients to make a pill.

That's not exactly accurate, either. (Though we'd all like to think so!)

Glad you're going to call the doctor, K. Were I in a similar position, I would try to follow up with another doctor locally, if at all possible.

Maybe you can find or someone can direct you to the information posted here by Otter about baclofen withdrawal information? I'm pretty sure he started a single thread related to it, and shouldn't be hard to find. Might also be in the Consolidated Baclofen Information thread.

Hang in there!

[keenegear89]

I really need help fast!

Dr. L hooked me up with a prescription today thank god! So everything is good now. That was very easy to do and he's a nice dude. Thanks for all the help and the suggestions! Hope you all the best.

[Cashregister]

I really need help fast!

desperados;1367706 wrote: Cashy, in regards to active ingredient apparently generic drugs in North america are allowed to be within a range between 80% - 120% in comparison to the the original brand.

That's a margin of...merely... 40%!!!

Ok it is not in Australia.

[Cashregister]

I really need help fast!

[QUOTE=Ne/Neva Eva;1367442]That's not accurate.

That's not exactly accurate either



What's this - twaddle? :Baclofen Dosage - a baclofen pump differs in dosage but I presume you don't have one? Need more info for baclofen for muscle spasticity just ask.

Did I mention i have actually taken it for an approved condition not off label???

And generic is generic in oz under law:
The regulatory boards in Canada, Israel, Chile, Australia & the UK all require that generic medications have the same active ingredients, quality, strength, purity, & stability as brand name medications.

If you want a refereed article ask away.

Lucky us it's not wishful thinking at all.

[Cashregister]

I really need help fast!

desperados;1367706 wrote: Cashy, in regards to active ingredient apparently generic drugs in North america are allowed to be within a range between 80% - 120% in comparison to the the original brand.

That's a margin of...merely... 40%!!!

It's not go back to science class this is such an urban myth


Can the bioavailability of bioequivalent products differ by up to 40%?

No, for two drugs to be bioequivalent, the 90% confidence intervals (90% CI) for the ratio of each pharmacokinetic parameter, Cmax and AUC, must lie within the range 0.8-1.25 (sometimes also expressed as 80-125%).

The 90% CI of 0.8-1.25 is a numerical index and not a direct measure of the difference in systemic concentrations of the active ingredient resulting from administration of the two products. It does not mean that the Cmax and AUC ratios estimated for each formulation can vary by -20 to +25%. In reality, for a product to fit within these relatively tight confidence limits the mean AUC and Cmax must be very close, and any difference in bioavailability is certainly less than 10%.4