Hi everyone,
I went through the consolidated baclofen information thread, fixed up the dead links, added some content that has come to light since and added it here. If anyone has some useful additions let me know and ill incorporate them.
Books by Dr Ameisen- Suppression of Alcohol Dependence Using Baclofen: A 2-Year Observational Study of 100 Patients
- New study on baclofen "a success rate of 68%"
- BACLOFEN EFFICACY IN REDUCING ALCOHOL CRAVING AND INTAKE: A PRELIMINARY DOUBLE-BLIND RANDOMIZED CONTROLLED STUDY Alcohol and Alcoholism Vol. 37, No. 5, pp. 504-508, 2002Role of the GABAB receptor system in alcoholism and stress: focus on clinical studies and treatment perspectivesEffectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study.Suppression de la dependance a l’alcool et de la consommation
d’alcool par le baclofene a haute dose : un essai en ouvert
Annales Medico-PsychologiquesTwo studies showing the safety of high dose baclofen
Case Reports
French wikipedia entry which has much more useful information (translate to English)English wikipedia entryClinical Experience with Baclofen in the Management of Alcohol-Dependent Patients with Psychiatric Comorbidity: A Selected Case SeriesComplete and prolonged supression of symptoms and consequences of alcohol-dependence using high-dose baclofen: a self-case report of a physician Oliver AmeisenSupression of symptoms of alcohol dependence and craving using high-dose baclofen William Bucknam Alcohol and Alcoholism 2007
Videos
I went through the consolidated baclofen information thread, fixed up the dead links, added some content that has come to light since and added it here. If anyone has some useful additions let me know and ill incorporate them.
Books by Dr Ameisen
- End of my addiction - is a must read for anyone interested in baclofen
- heal thyself
Prescribing guide
- pharmacological hypothesis of how baclofen reduces cravings for alcohol
- What to do if you are running low on (or out of) baclofen
Studies
d’alcool par le baclofene a haute dose : un essai en ouvert
Annales Medico-PsychologiquesTwo studies showing the safety of high dose baclofen
Case Reports
French wikipedia entry which has much more useful information (translate to English)English wikipedia entryClinical Experience with Baclofen in the Management of Alcohol-Dependent Patients with Psychiatric Comorbidity: A Selected Case SeriesComplete and prolonged supression of symptoms and consequences of alcohol-dependence using high-dose baclofen: a self-case report of a physician Oliver AmeisenSupression of symptoms of alcohol dependence and craving using high-dose baclofen William Bucknam Alcohol and Alcoholism 2007
Videos
- An interview with Dr. Ameisen - the first doctor in this news clip, Dr James Garbutt, is a researcher that did a study with alcoholic patients and low dose baclofen (3x10mg/day). He found that it was effective, but not completely successful. Dr. Ameisen lost all craving for alcohol when he reached a dose of 270mg/day, nine times the dose used In the study. He continues to take 50mg/day now, five years later:
- http://www.youtube.com/watch?v=byain0Vo5mo[/video]]YouTube video of PET scan showing reduced cocaine craving in the brain Baclofen works for alcohol craving via the same mechanism:
Discussion forums
Other useful links
- Finding out about baclofen trials and participating as a subjectBaclofen and beyond - GABAB receptor agonists for use in the treatment of alcohol use disorder: preclinical and clinical evidenceBaclofen Approved in FranceDr. Phillip Thomas' website lots of useful information about baclofenBaclofenuk.com another informational websiteConsolidated Baclofen Success Thread
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