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Ketamine’s Antidepressant Efficacy is extended 4 weeks with a family history of AUD
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Ketamine’s Antidepressant Efficacy is extended 4 weeks with a family history of AUD
01-01-2014 - Indifference reached, success with high dose Baclofen 295mg.
Baclofen prescribing guide
Baclofen for alcoholism - Consolidated Information - Studies, prescribing guides, linksTags: None
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Just read this, interesting. -tk
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Ketamine...That was in the news a lot in years gone by. This study was only of 54 people, and it included a group on placebo (so not many actually getting ketamine), but it's still interesting. The conclusion:
Results: FHP subjects randomized to placebo had a greater antidepressant response than FHN subjects; however, contrary to our
initial hypothesis, there was no significant difference in antidepressant efficacy with riluzole. Although potentially underpowered,
there was no difference in overall time-to-relapse based on randomization status (riluzole responders: n*=*15, placebo responders:
n*=*17). Yet, time-to-relapse was longer in FHP placebo responders (n*=*8) compared to FHN placebo responders (n*=*9) with, again,
no significant difference in time-to-relapse in FHP riluzole responders (n*=*6) compared to FHN riluzole responders (n*=*9).
Conclusions: Ketamine??s extended antidepressant durability in FHP TRD should be considered in the design and analysis of
ketamine depression trials.
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