I looiked into this because we are caring for a 91 year old blind, deaf lady who has no family to look after her. She can't walk and is suffering from what appears to be dementia. I think it is largely anxiety related however. It's a real challenge as she is also incontginent and the whole thing makes her quite depressed and sometimes hard to deal with. She has a lot of aches and pains so it's hard to say whether she is groaning and rolling her eyes in pain because of a dementia condition, depression, some kind of pain or just a bit of wind in her stomach.
In any event, I think it shows that this re-discovery of new purposes of old drugs his highly significant and that a lot of "illnesses" are actually just a product of neurological deficit, which is why Ameisen was credited with discovering a cure for poly-drug addiction.